Fernanda B. Leal

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BACKGROUND Successful gametogenesis requires the establishment of an appropriate epigenetic state in developing germ cells. Nevertheless, an association between abnormal spermatogenesis and epigenetic disturbances in germline-specific genes remains to be demonstrated. METHODS In this study, the DNA methylation pattern of the promoter CpG island (CGI) of(More)
AIM To determine the correlation between leakage and sealer penetration into dentinal tubule. METHODOLOGY The root canal of 60 mandibular central incisor teeth were prepared and filled under standardized conditions. Teeth were placed into a device to assess glucose penetration using 15 psi pressure application. After 1 h, glucose concentrations in the(More)
OBJECTIVES To perform a longitudinal analysis of the effect of four substances (citric acid at 1%, 5% and 10% concentrations and 17% EDTA) on dentin. METHODS Sixteen human molars had their crowns removed exposing cervical root dentin. A grinding procedure was used to produce a standardized smear layer and to create a smooth surface for analysis.(More)
In order to assess the possible influence of gonadotrophin-releasing hormone analogue and human menopausal gonadotrophin on the occurrence of fractured zona oocytes (FZOs) in in-vitro fertilization (IVF) treatment cycles, we analysed 267 consecutive cycles in 199 patients. In 87 cycles, at least one fractured zona oocyte was recovered, and in 180 cycles(More)
In a retrospective study we have reviewed the data of 570 consecutive IVF cycles in which a GnRH agonist (GnRHa) was started in the early follicular phase (long protocol). Cycles were divided in groups according to estradiol levels before HMG administration: A, <20 pg/ml; B, 20 to 50pg/ml; C, 51 to 100pg/ml. Our objective was to determine if the degree of(More)
AIM To compare the ability of Ceramicrete, BioAggregate and white ProRoot MTA (mineral trioxide aggregate) to prevent glucose leakage through root-end fillings. METHODOLOGY After root canal instrumentation, the apical 3 mm of maxillary incisors were resected and retropreparations, 3 mm in depth, were created with ultrasound. Root-end cavities were filled(More)
OBJECTIVES This study evaluated the performance of phenylbis (2,4,6-trimethylbenzoyl)-phosphine oxide (BAPO) as an alternative photoinitiator in the polymerization kinetics (PK), flexural strength (σ) and elastic modulus (E) of a model dental resin. METHODS A monomer mixture based on Bis-GMA and TEGDMA was used as model dental resin. Initially a screening(More)
Fifty six grapevine varieties traditionally grown in the Northwest region of the Iberian Peninsula were analysed for six microsatellite loci, in order to determine the relationships among them as well as the plant material that should be collected and preserved in germplasm banks. Previous morphological and molecular results were taken into account for(More)
This study assessed the effect of BioPure MTAD on the sealing ability on the basis of the filtration rate of glucose along the root fillings. Both 17% ethylenediaminetetraacetic acid (EDTA) and smear-covered dentin were used as reference patterns to compare the results. Sixty-four human upper incisors were prepared with different irrigation protocols (n =(More)
We read with interest the recent article by Swartz et al. [1999] on vascular abnormalities in Adams-Oliver syndrome (AOS). Although the pathogenesis of this predominantly autosomal-dominant syndrome remains unclear, it has been suggested [Hoyme et al., 1982] that intrauterine vascular disruption involving small-caliber vessels may be responsible for(More)