Ferenc Pongrácz

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1. The role of synaptic activation of NMDA (N-methyl-D-aspartate) receptor-mediated conductances on CA1 hippocampal pyramidal cells in short-term excitability changes was studied with the use of a computational model. Model parameters were based on experimental recordings from dendrites and somata and previous hippocampal simulations. Representation of CA1(More)
1. Experimental studies employing whole cell patch recordings from freshly isolated olfactory sensory neurons of the salamander (Ambystoma tigrinum) yield much higher estimates of specific membrane resistance (Rm) than studies using conventional intracellular recordings from in situ neurons. Because Rm is critical for understanding information transfer in(More)
Epileptogenic activity was induced by topical application of 3-Ap on the somatosensory cortex of anaesthetized cats. Surface epileptiform events were recorded and single cell activity was studied with intracellular electrodes both in the primary and in the mirror focus. Surface records showed that soon after the onset of paroxysmal activity in the primary(More)
Exact probability analysis of the spontaneous bursting activity of epileptic units is a common problem. A microcomputer method, suitable for the calculation of the scalar function of two variables of the spike occurrence of this type of discharge, has been developed. The time measured from the first spike of a burst and the duration of the preceding(More)
An analytical, recursive method has been developed to demonstrate the anisotropic electrotonic geometry of nerve cells containing varicose or spiny dendrites. The procedure has been based on the distribution of the core geometry of dendrites into modules which consist of module elements where the physical length is much shorter than the actual space(More)