Ferenc Pongrácz

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1. The role of synaptic activation of NMDA (N-methyl-D-aspartate) receptor-mediated conductances on CA1 hippocampal pyramidal cells in short-term excitability changes was studied with the use of a computational model. Model parameters were based on experimental recordings from dendrites and somata and previous hippocampal simulations. Representation of CA1(More)
An analytical, recursive method has been developed to demonstrate the anisotropic electrotonic geometry of nerve cells containing varicose or spiny dendrites. The procedure has been based on the distribution of the core geometry of dendrites into modules which consist of module elements where the physical length is much shorter than the actual space(More)
The electrotonic structure of lobster olfactory receptor cells was evaluated using general purpose simulation software in a compartmental model derived from electron-microscopic reconstruction. The model with non-uniform membrane resistance (Rm) was used to (i) simulate current spread and (ii) determine if the electronic structure of the cell improves(More)
Passive electrotonic activity of anatomically complex nerve cells has been computed through a simplified anisotropic "smoothing" of the original structures. The algorithm for this "smoothing" involves a recursive matching of the amplitude, zero and pole of the input impedances for each segment. This algorithm can be used for both spatially and/or(More)
The computational background for analysing the passive, subthreshold properties of fine-scale ramifications such as "en-passant" and "terminal ladder" type chains of boutons and spiny dendrites is presented. The segment-by-segment approximation of a cable composed of serial or parallel chains of identical units (modules) is based on the cable(More)