Fengling Song

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Currently, no drugs are available to protect humans from γ-irradiation-induced death. Because reactive oxygen species are produced upon exposure to γ-irradiation and directly responsible for the resulting death, we hypothesized that antioxidants found in foodstuffs may provide a safe and potent means of antioxidant-dependent radioprotection. Here, we(More)
Recent years have witnessed the development of many fluorescence methods to detect mercury ion because mercury continues to be a major environmental and health concern. While some probes for Hg2+ are based on the coordination of multiple nitrogen atoms with the metal ion, the majority of probes for Hg2+ are based on extremely strong Hg-S binding. Despite(More)
Metal analyses in chemistry, materials science, and environmental science are currently performed using techniques such as inductively coupled plasma mass spectrometry and X-ray fluorescence, which require expensive instrumentation and are not high-throughput. Although fluorescent probes are known for their sensitivity and specificity and are amenable to(More)
Residual metals in fine chemicals are currently detected by using inductively coupled plasma mass spectrometry, which requires expensive instrumentation and does not have high-throughput capabilities. Although fluorescent probes can be amenable to high-throughput analyses of metals, the utility of such analyses is limited due to the lack of generality.(More)
Ring chromosome 3, r(3), is an extremely rare cytogenetic abnormality with clinical heterogeneity and only 12 cases reported in the literature. Here, we report a 1-year-old girl presenting distinctive facial features, developmental delay, and congenital heart defects with r(3) and a ∼10-Mb deletion of chromosome 3pterp25.3 (61,891-9,979,408) involving 42(More)
Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are neurogenetic disorders caused by loss of function of the imprinted genes at 15q11q13. A 5-7 Mb paternal/maternal deletion of chromosomal region 15q11.2q13 is the major genetic cause of PWS/AS, but in a small group of patients, the PWS/AS phenotype can result from maternal/paternal uniparental disomy(More)
OBJECTIVE To investigate the genetic cause for a child with developmental delay and congenital heart disease through molecular cytogenetic analysis. METHODS G-banded karyotyping and chromosomal microarray analysis (CMA) were performed for the patient and his parents. RESULTS The proband's karyotype was detected as ring chromosome 3, and a 3q26.3-25.3(More)
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