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Traditional Chinese Medicine Preparations (TCMPs) contain massive numbers of ingredients responsible for their multiple efficacies. An absorption-based quality control method for complicated TCMPs using Hu-gan-kang-yuan Capsule (HGKYC) as an example was developed. To select proper chemical markers for quality control of HGKYC, an ultra-fast liquid(More)
Wogonin and oroxylin A in Scutellariae Radix, schisandrin in Chinensis Fructus, paeoniflorin in Moutan Cortex and emodin in Polygoni Cuspidate Rhizome et Radix are anti-inflammatory active compounds. A method for simultaneous determination of the five compounds in rat was developed and validated using high-performance liquid chromatography with tandem mass(More)
OBJECTIVE To study the preparation of the sustained-released capsule of Gegen isoflavones (SRCGI) and choose the best prescription. METHODS EC and HPMC were used as sustained-released excipients. Uniform layout test was employed to design the formulation. RESULTS The best prescription release drug Q0.5h = 50% - 53%, to 100% at 12h and its dissolution(More)
OBJECTIVE To develop a GC-MS method for the determination of cinnamaldehyde and study on the influence of decoction methods and compatibility on the contents of cinnamaldehyde in Mahuang decoction. METHODS Gas chromatography-mass spectrometry (GC-MS) was used. Chromatography/mass spectrometric conditions were: capillary column DB-17 (30 m x 0.5 mm, 0.25(More)
Radix Phytolaccae (the dried root of Phytolacca acinosa Roxb. or Phytolacca americana L.) is widely used in East Asian countries for the treatment of inflammation-related diseases. The active component of Radix Phtolaccae is Phytolcaccagenin a triterpenoid saponin. Phytolcaccagenin has anti-inflammatory activities that exceed those of Esculentoside A and(More)
Emodin (1,3,8-trihydroxy-6-methylanthraquinone) has been identified to have the potential to improve lung fibrosis and lung cancer. To avoid the liver and kidney toxicities and the fast metabolism of emodin, emodin-loaded polylactic acid microspheres (ED-PLA-MS) were prepared and their characteristics were studied. ED-PLA-MS were prepared by the organic(More)
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