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Immunosuppression promotes endogenous neural stem and progenitor cell migration and tissue regeneration after ischemic injury
Recent work has demonstrated that self-repair in the adult brain can be augmented by the infusion of growth factors to activate endogenous neural precursor cells that contribute to new tissueExpand
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NogoR1 and PirB Signaling Stimulates Neural Stem Cell Survival and Proliferation
Neural stem cells (NSCs) and neural progenitors (NPs) in the mammalian neocortex give rise to the main cell types of the nervous system. The biological behavior of these NSCs and NPs is regulated byExpand
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Primitive Neural Stem Cells in the Adult Mammalian Brain Give Rise to GFAP-Expressing Neural Stem Cells
Summary Adult forebrain definitive neural stem cells (NSCs) comprise a subpopulation of GFAP-expressing subependymal cells that arise from embryonic fibroblast growth factor (FGF)-dependent NSCs thatExpand
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The use of Nasal Epithelial Stem/progenitor Cells to Produce Functioning Ciliated Cells in vitro
Background Although epithelial stem/progenitor cells have been isolated from many parts of the human airway epithelium such as lung and trachea, there is limited information in regard to stem cellsExpand
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Establishing Clonal Cell Lines with Endothelial-Like Potential from CD9hi, SSEA-1− Cells in Embryonic Stem Cell-Derived Embryoid Bodies
Background Differentiation of embryonic stem cells (ESCs) into specific cell types with minimal risk of teratoma formation could be efficiently directed by first reducing the differentiationExpand
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Notch signaling imparts and preserves neural stem characteristics in the adult brain.
Although the role of Notch has been studied extensively in the developing nervous system, the embryonic lethality of Notch pathway mutants has hindered studies in the adult brain. The creation ofExpand
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Cancer stem cells in nasopharyngeal carcinoma: current evidence
Nasopharyngeal carcinoma (NPC) is highly prevalent in southern China and Southeast Asia. Cancer resistance to therapy, metastasis and disease recurrence are significant hurdles to successfulExpand
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