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The increasing use of information technology (IT) has resulted in a need for evaluating the productivity impacts of IT. The contemporary IT evaluation approach has focused on return on investment and return on management. IT investment has impacts on different stages of business operations. For example, in the banking industry, IT plays a key role in(More)
We study a new image sensor that is reminiscent of a traditional photographic film. Each pixel in the sensor has a binary response, giving only a 1-bit quantized measurement of the local light intensity. To analyze its performance, we formulate the oversampled binary sensing scheme as a parameter estimation problem based on quantized Poisson statistics. We(More)
BACKGROUND Somatostatin analogues are commonly used to treat symptoms associated with hormone hypersecretion in neuroendocrine tumors; however, data on their antitumor effects are limited. METHODS We conducted a randomized, double-blind, placebo-controlled, multinational study of the somatostatin analogue lanreotide in patients with advanced,(More)
An appropriate performance measurement system is an important requirement for the effective management of a supply chain. Two hurdles are present in measuring the performance of a supply chain and its members. One is the existence of multiple measures that characterize the performance of chain members, and for which data must be acquired; the other is the(More)
In this study, we evaluated a concatenated low pH (pH 3) and high pH (pH 10) reversed-phase liquid chromatography strategy as a first dimension for two-dimensional liquid chromatography tandem mass spectrometry ("shotgun") proteomic analysis of trypsin-digested human MCF10A cell sample. Compared with the more traditional strong cation exchange method, the(More)
We investigate the problem of diagnostic lung nodule classification using thoracic Computed Tomography (CT) screening. Unlike traditional studies primarily relying on nodule segmentation for regional analysis, we tackle a more challenging problem on directly modelling raw nodule patches without any prior definition of nodule morphology. We propose a(More)
A cycle time-throughput (CT-TH) curve plays an important role in strategic planning for manufacturing systems. In this research, we seek to quantify the relationship of the moments and percentiles of cycle time to throughput rate via simulation experiments. The estimation of CT-TH moment curves is based on a nonlinear regression metamodel supported by(More)