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Long-read sequencing and de novo assembly of a Chinese genome
TLDR
Long-read sequencing of the transcriptome reveals novel spliced genes that are not annotated in GENCODE and are missed by short-read RNA-Seq, implying that improved characterization of genome functional variation may require the use of a range of genomic technologies on diverse human populations. Expand
Detection of IgM and IgG antibodies in patients with coronavirus disease 2019
This study aimed to determine the IgM and IgG responses against severe acute respiratory syndrome coronavirus (SARS‐CoV)‐2 in coronavirus disease 2019 (COVID‐19) patients with varying illnessExpand
Circulating miR-30a, miR-126 and let-7b as biomarker for ischemic stroke in humans
TLDR
Data suggest thatmiR-30a, miR-126 and let-7b might be useful biomarkers for ischemic stroke in humans. Expand
Effect of sourdough fermentation on the quality of Chinese Northern-style steamed breads
Abstract The effect of spontaneous and lactic acid bacteria (LAB) fermentation ( Lactobacillus plantarum (LP), Lactobacillus sanfranciscensis (LS), Lactobacillus brevis (LBr) and LactobacillusExpand
Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts.
TLDR
It is demonstrated that engagement of Tim-3 by mouse recombinant Galectin-9 remarkably suppresses allograft rejection and improves survival of allogeneic skin grafts and could lead to developing novel therapies in transplant medicine. Expand
The Role of Caveolin-1 in Blood–Brain Barrier Disruption Induced by Focused Ultrasound Combined with Microbubbles
TLDR
Treatment with FUS, in combination with a dose of microbubbles, can enhance BBB permeability through a caveolae-mediated transcellular approach by upregulating the expression level of caveolin-1 and, consequently, the amount of Caveolae. Expand
Obesity predisposes to the risk of higher mortality in young COVID‐19 patients
TLDR
The data support that obesity could be a risk factor associated with high mortality in young COVID‐19 patients, whereas aggravated inflammatory response, enhanced cardiac injury, and increased coagulation activity are likely to be the mechanisms contributing to the high mortality. Expand
Blocking TREM-1 signaling prolongs survival of mice with Pseudomonas aeruginosa induced sepsis.
TLDR
The results showed that TREM-1 could be a potential therapeutic target for bacterial sepsis by leading to significant reduction of pro-inflammatory mediators such as IL-1, TNF-α, MCP-1 and IFN-γ. Expand
Galectin-9 Significantly Prolongs the Survival of Fully Mismatched Cardiac Allografts in Mice
TLDR
A short-course administration of galectin-9 significantly prolonged the survival of fully allogeneic cardiac allografts, which was associated with the suppression of Th1 and Th17 immune responses. Expand
Identification of cardiac-related circulating microRNA profile in human chronic heart failure
TLDR
This study provides global profiles of miRNAs changes in plasma and failing heart, and using a circulation-tissue miRNA profiling comparison model, successfully identifies 3 cardiac-related circulating mi RNAs as potential biomarkers for diagnosis of heart failure. Expand
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