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TRAIL/Apo-2L is a member of the tumor necrosis factor superfamily and has recently been shown to induce apoptosis in cancer cells, but not in normal cells. In nude mice injected with human tumors, TRAIL reduces the size of these tumors without side effects. Akt promotes cell survival and block apoptosis. Some prostate cancer cells express high levels of Akt(More)
Tumor necrosis factor superfamily member TRAIL/Apo-2L has recently been shown to induce apoptosis in transformed and cancer cells. Some prostate cancer cells express constitutively active Akt/protein kinase B due to a complete loss of lipid phosphatase PTEN gene, a negative regulator of phosphatidylinositol 3-kinase pathway. Constitutively active Akt(More)
The positive real lemma provides the basis for constructing linear output feedback dynamic compensators for multi-input plants with independent amplitude saturations. Fixed-structure techniques are used to obtain full-and reduced-order feedback compensators along with a guaranteed domain of attraction. These results are then applied to the problem of rate(More)
  • Feng Tyan
  • 2003
Since the proportional navigation guidance law was first introduced, many of the researchers had proposed different methodologies to investigate the corresponding performances of all the existing guidance laws. In 1997, Yang and Yang introduced an unified approach, in that paper the authors found that under the proposed framework, all the existing guidance(More)
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The three dimensional PPN guidance against a high speed-nonmaneuvering target is analyzed. A necessary and sufficient conditions for the missile to capture the target are obtained. The result is more general than those which presented previously. Furthermore, the capture region and criterion of finite LOS turn rate are found and shown in three-dimensional(More)