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Over the last decade, the introduction of microarray technology has had a profound impact on gene expression research. The publication of studies with dissimilar or altogether contradictory results, obtained using different microarray platforms to analyze identical RNA samples, has raised concerns about the reliability of this technology. The MicroArray(More)
With the recent advent of 4G LTE networks, there has been increasing interest to better understand the performance and power characteristics, compared with 3G/WiFi networks. In this paper, we take one of the first steps in this direction. Using a publicly deployed tool we designed for Android called 4GTest attracting more than 3000 users within 2 months(More)
With lower latency and higher bandwidth than its predecessor 3G networks, the latest cellular technology 4G LTE has been attracting many new users. However, the interactions among applications, network transport protocol, and the radio layer still remain unexplored. In this work, we conduct an in-depth study of these interactions and their impact on(More)
3G cellular data networks have recently witnessed explosive growth. In this work, we focus on UMTS, one of the most popular 3G mobile communication technologies. Our work is the first to accurately infer, for any UMTS network, the state machine (both transitions and timer values) that guides the radio resource allocation policy through a light-weight(More)
In a recent report, [Zhang et al. (2003) N. Engl. J. Med. 348, 203-213], the presence of CD3+ tumor-infiltrating lymphocytes (TILs) was found to correlate with improved survival in epithelial ovarian cancer. We performed immunohistochemical analysis for TILs and cancer testis antigens in 117 cases of epithelial ovarian cancer. The interrelationship between(More)
Gene expression data from microarrays are being applied to predict preclinical and clinical endpoints, but the reliability of these predictions has not been established. In the MAQC-II project, 36 independent teams analyzed six microarray data sets to generate predictive models for classifying a sample with respect to one of 13 endpoints indicative of lung(More)
Modern virtual machines often maintain multiple compiled versions of a method. An on-stack replacement (OSR) mechanism enables a virtual machine to transfer execution between compiled versions, even while a method runs. Relying on this mechanism, the system can exploit powerful techniques to reduce compile time and code space, dynamically de-optimize code,(More)
The rat has been used extensively as a model for evaluating chemical toxicities and for understanding drug mechanisms. However, its transcriptome across multiple organs, or developmental stages, has not yet been reported. Here we show, as part of the SEQC consortium efforts, a comprehensive rat transcriptomic BodyMap created by performing RNA-Seq on 320(More)
Cellular networks employ a specific radio resource management policy distinguishing them from wired and Wi-Fi networks. A lack of awareness of this important mechanism potentially leads to resource-inefficient mobile applications. We perform the first network-wide, large-scale investigation of a particular type of application traffic pattern called periodic(More)
Transcription factor Nuclear Factor One (NFI) proteins are derived from a small family of four vertebrate genes (NFIA, B, C and X), all of which produce a fair number of protein variants by alternative splicing. In order to ultimately locate RNA signal sequences around exon/intron borders for the production of regulated splice variants, we have determined(More)