Felipe Santos

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Recent animal work has suggested that cochlear synapses are more vulnerable than hair cells in both noise-induced and age-related hearing loss. This synaptopathy is invisible in conventional histopathological analysis, because cochlear nerve cell bodies in the spiral ganglion survive for years, and synaptic analysis requires special immunostaining or(More)
HYPOTHESIS It is possible to implant a stimulating electrode array in the semicircular canals without damaging rotational sensitivity or hearing. The electrodes will evoke robust and precisely controlled eye movements. BACKGROUND A number of groups are attempting to develop a neural prosthesis to ameliorate abnormal vestibular function. Animal studies(More)
OBJECTIVE To describe the temporal bone histopathology in children with congenital toxoplasmosis. BACKGROUND Toxoplasmosis is a parasitic infection caused by Toxoplasma gondii. If fetal infection occurs early in gestation, severe inflammation and necrosis can cause brain lesions, chorioretinitis, and hearing loss. Hearing loss in congenital toxoplasmosis(More)
BACKGROUND Osteogenesis Imperfecta (OI) is a genetic disorder of connective tissue matrix. OI is caused by mutations that affect type I collagen. The hearing loss in OI is characterized by onset in early adulthood and can be conductive, sensorineural, or mixed. OBJECTIVES To describe the temporal bone histopathology in 9 individuals with OI. MATERIALS(More)
Coluna vertebral, postura/epidemiologia, saúde do adolescente, saúde escolar, Brasil. RESUMO As doenças nas costas, mais especifi-cadamente as dores na região lombar (lombalgia), são muito prevalentes na população adulta (1) e também na po-pulação adolescente (2). Muitas vezes, a ocorrência da lombalgia precede ou é
OBJECTIVE To describe results in a large series of patients using a recent variation of hypoglossal-facial nerve anastomosis (HFA) in which the intratemporal facial nerve segment is used, obviating the need for a sensory nerve "jump graft." STUDY DESIGN Retrospective chart review. SETTING Tertiary neurotologic referral center. PATIENTS Nineteen(More)
OBJECTIVE To describe the temporal bone histopathology of vasculitis in granulomatosis with polyangitis. BACKGROUND Granulomatosis with polyangitis is an autoimmune disease that presents as granulomatosis and vasculitis. Otologic findings, including otitis media, hearing loss, vertigo, and facial paralysis are common in this condition. MATERIAL AND(More)
The authors report a case of neurofibromatosis Type 2 presenting with symptoms of trigeminal neuralgia refractory to medical management following placement of an auditory brainstem implant (ABI). Physical examination and history revealed trigeminal neuralgia. A 3D FIESTA (fast imaging employing steady-state acquisition) MR imaging study demonstrated(More)