Felipe P. G. Bergo

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The absence of object information very often asks for considerable human assistance in medical image segmentation. Many interactive two-dimensional and three-dimensional (3-D) segmentation methods have been proposed, but their response time to user's actions should be considerably reduced to make them viable from the practical point of view. We circumvent(More)
BACKGROUND AND PURPOSE In Friedreich's ataxia (FRDA), frataxin deficiency results in iron redistribution in the dentate nuclei (DNC). Clusters of iron cause inhomogeneities in a magnetic field and result in a reduction in T2 relaxation time (T2). METHODS T2 was prospectively evaluated in DNC, putamen, substantia nigra (SN), cerebellar white matter (CWM)(More)
The Image Foresting Transform (IFT) is a tool for the design of image processing operators based on con-nectivity, which reduces image processing problems into an optimum-path forest problem in a graph derived from the image. A new image operator is presented, which solves segmentation by pruning trees of the forest. An IFT is applied to create an(More)
Focal cortical dysplasia is the most common malformation in patients with intractable epilepsy. The segmentation of FCD lesions in MR-T1 images of the brain is a crucial step for treatment planning. In this work we present a new FCD segmentation technique based on analysis of texture asymmetry. This technique does not rely on template-based segmen-tation(More)
Although white matter damage may play a major role in the pathogenesis of spinocerebellar ataxia 3 (SCA3), available data rely exclusively upon macrostructural analyses. In this setting we designed a study to investigate white matter integrity. We evaluated 38 genetically-confirmed SCA3 patients (mean age, 52.76 ± 12.70 years; 21 males) with clinical scales(More)
Although Friedreich’s ataxia is characterized by spinal cord atrophy, it remains to be investigated the possible correlation of such atrophy with clinical disability and genetic parameters. Thirty-three patients with Friedreich’s ataxia and 30 healthy controls underwent MRI on a 3 T scanner. We used T1-weighted 3D images to estimate spinal cord area and(More)
The Image Foresting Transform (IFT) has been proposed for the design of image operators based on connectivity. The IFT reduces image processing problems into a minimum-cost path forest problem in a graph derived from the image. It has been successfully used for image filtering, segmenta-tion, and analysis. In this work, we propose a novel image operator(More)
Our objective was to investigate spinal cord (SC) atrophy in amyotrophic lateral sclerosis (ALS) patients, and to determine whether it correlates with clinical parameters. Forty-three patients with ALS (25 males) and 43 age- and gender-matched healthy controls underwent MRI on a 3T scanner. We used T1-weighted 3D images covering the whole brain and the(More)