Felicia Stern

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OBJECTIVE To evaluate the vitamin status and the effects of micronutrient supplementation as determined by biochemical assays and functional, cognitive and emotional tests in a selected well-established group of elderly people, average age above 80 years. METHODS Dietary consumption was evaluated by in-person interview using a food frequency(More)
To measure the activation coefficient (AC) of erythrocyte glutathione reductase (GR), suspended whole blood was lysed in a preincubation solution, with or without 100 microM flavin adenine dinucleotide (FAD). Upon addition of the reaction mixture, FAD concentration decreased about 10-fold. No AC values < 1 were obtained in any of the subjects. The range of(More)
OBJECTIVE To evaluate the distribution pattern of the main macronutrients (protein, fat, carbohydrates) and fiber in a selected well-established group of elderly people, average age above 80 years. METHOD Dietary consumption was evaluated in a well-established group of 21 elderly people in a home for the aged by in-person interview using a food frequency(More)
(1) Changes during development in the levels of proteinases and peptidases were measured in brain homogenates. At all ages di- and tripeptidase levels were 7-15-fold higher than proteinase activity. (2) Cathepsin A and D and neutral proteinase activity first decreased (during the 5 days before birth) and then increased (primarily during the first 10 days(More)
BACKGROUND Inadequate food intake in old age can lead to marginal or suboptimal nutrient intakes causing the deterioration of physiological and health states. OBJECTIVE To describe, by intake assessment, nutritional status of institutionalized elderly and to compare the data to other studies findings. DESIGN Dietary intake was assessed in 50 (18 males,(More)
Conditions for extraction of rat brain soluble and particulate cysteine proteinase inhibitors (CPIs) were compared and an optimal one was selected to isolate low- and high-molecular-weight forms active toward papain or brain cathepsins B/L. The different forms were purified by affinity chromatography on alkylated papain, and identified on sodium dodecyl(More)