Felice Beitzel

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Beta(2)-adrenoceptor agonists such as fenoterol are anabolic in skeletal muscle, and because they promote hypertrophy and improve force-producing capacity, they have potential application for enhancing muscle repair after injury. No previous studies have measured the beta(2)-adrenoceptor population in regenerating skeletal muscle or determined whether(More)
Beitzel F, Sillence MN, Lynch GS. -Adrenoceptor signaling in regenerating skeletal muscle after -agonist administration. Am J Physiol Endocrinol Metab 293: E932–E940, 2007. First published July 10, 2007; doi:10.1152/ajpendo.00175.2007.—Stimulating the -adrenoceptor ( -AR) signaling pathway can enhance the functional repair of skeletal muscle after injury,(More)
Intramuscular injection of bupivacaine causes complete degeneration of fibers in extensor digitorum longus (EDL) muscles of rats, followed by complete regeneration within 60 days. Previous studies have shown that regenerated EDL muscles are protected from contraction-induced injury 60 days after bupivacaine injection. It is possible that these regenerated(More)
Aging is associated with a slowing of skeletal muscle contractile properties, including a decreased rate of relaxation. In rats, the age-related decrease in the maximal rate of relaxation is reversed after 4-wk administration with the beta2-adrenoceptor agonist (beta2-agonist) fenoterol. Given the critical role of the sarcoplasmic reticulum (SR) in(More)
Stimulating the beta-adrenoceptor (beta-AR) signaling pathway can enhance the functional repair of skeletal muscle after injury, but long-term use of beta-AR agonists causes beta-AR downregulation, which may limit their therapeutic effectiveness. The aim was to examine beta-AR signaling during early regeneration in rat fast-twitch [extensor digitorum longus(More)
Schertzer, Jonathan D., David R. Plant, James G. Ryall, Felice Beitzel, Nicole Stupka, and Gordon S. Lynch. 2-Agonist administration increases sarcoplasmic reticulum Ca -ATPase activity in aged rat skeletal muscle. Am J Physiol Endocrinol Metab 288: E526–E533, 2005. First published October 12, 2004; doi:10.1152/ ajpendo.00399.2004.—Aging is associated with(More)
AIM To investigate the presence of myosin heavy chain isoforms in human masseter muscle and to describe any differences in orthognathic surgery patients with different mandibular plane angles. METHOD Biopsies were obtained from the anterior border of the superficial masseter muscle in 18 patients undergoing various orthognathic procedures. Myosin heavy(More)
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