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CD40 gene polymorphisms confer risk of Behcet's disease but not of Vogt-Koyanagi-Harada syndrome in a Han Chinese population.
OBJECTIVES Recent genetic surveys including a genome-wide association study have identified CD40 as a susceptibility gene for several autoimmune diseases. This study was designed to investigate theExpand
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Genetic Variation in the REL Gene Increases Risk of Behcet’s Disease in a Chinese Han Population but That of PRKCQ Does Not
Genome-wide association studies (GWAS) and candidate gene studies have identified the REL and PRKCQ genes as risk loci for various autoimmune diseases. The purpose of the present study was toExpand
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Polymorphisms of IL23R and Fuchs’ syndrome in a Chinese Han population
Purpose The aim of the study was to investigate the association of polymorphisms of the interleukin-23 receptor (IL23R) gene with Fuchs’ syndrome in a Chinese Han population. Methods ThreeExpand
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Replication study confirms the association between UBAC2 and Behçet's disease in two independent Chinese sets of patients and controls
IntroductionThe purpose of this study was to replicate genetic factors associated with the susceptibility to Behçet's disease (BD). We conducted a two-stage candidate genes association and functionalExpand
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CD40 polymorphisms in Han Chinese patients with Fuch uveitis syndrome
Purpose Polymorphisms of the cluster of differentiation 40 (CD40) gene have recently been identified to be associated with the risk to several immune diseases. The aim of this study was to determineExpand
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Clinical and Pathologic Features of a Suspected Selenium Deficiency in Captive Plains Zebras
Previous studies have shown that selenium (Se) deficiency is associated with nutritional myopathy, known as white muscle disease (WMD), in horses. However, correlations between Se deficiency andExpand
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[Establishment of an HBV chronic hepatitis B infection mouse model by vivo transduction of HBV cccDNA].
OBJECTIVE To generate a mouse model of chronic hepatitis B (CHB) infection by performing in vivo transduction of hepatitis B virus (HBV) covalently closed circular (ccc)DNA. METHODS Nude mice wereExpand
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[Blocking ERK signaling pathway lowers MMP-9 expression to alleviate brain edema after traumatic brain injury in rats].
OBJECTIVE To investigate the effects of blocking the activation of ERK pathway on the expression of matrix metalloproteinase-9 (MMP-9) and the formation of cerebral edema in SD rats after brainExpand
PRKCQ rs4750316 is associated with Vogt-Koyanagi-Harada syndrome in a Han Chinese population
Purpose The PRKCQ and REL genes are said to be associated with multiple autoimmune diseases. This study investigated the association between these genes and Vogt-Koyanagi-Harada (VKH) syndrome in HanExpand
[Blocking ERK signaling pathway lowers MMP-9 expression to alleviate brain edema after traumatic brain injury in rats].
OBJECTIVE To investigate the effects of blocking the activation of ERK pathway on the expression of matrix metalloproteinase-9 (MMP-9) and the formation of cerebral edema in SD rats after brainExpand