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Re-identification of individuals across camera networks with limited or no overlapping fields of view remains challenging in spite of significant research efforts. In this paper, we propose the use, and extensively evaluate the performance, of four alternatives for re-ID classification: regularized Pairwise Constrained Component Analysis, kernel Local(More)
VPS35, a major component of the retromer complex, is important for endosome-to-Golgi retrieval of membrane proteins. Although implicated in Alzheimer's disease (AD), how VPS35 regulates AD-associated pathology is unknown. In this paper, we show that hemizygous deletion of Vps35 in the Tg2576 mouse model of AD led to earlier-onset AD-like phenotypes,(More)
We have analyzed the inheritance and expression of a line of transgenic salmon harboring the antifreeze protein gene from the winter flounder. The genomic clone 2A-7 coding for a major liver-type antifreeze protein gene (wflAFP-6) was integrated into the salmon genome. From a transgenic founder (# 1469), an F3 generation was produced. In this study,(More)
Twitter has increasingly become an important source of information during disasters. Authorities have responded by providing related information in Twitter. The same information channel can also be used to deliver disaster preparation information to increase the disaster readiness of the general public. Retweeting is the key mechanism to facilitate this(More)
11Beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) catalyzes the conversion of 11-dehydrocorticosterone to its active form corticosterone in rodents (or cortisone to cortisol in humans). The reductive reaction of the 11-keto to 11-hydroxyl is the pivotal switch in the activation of glucocorticoids. An excess of active glucocorticoids has been shown to(More)
AIMS To better understand the role of oxidative stress in fetal programming, we assessed the hypothesis that the mitochondrial translocation of human telomerase reverse transcriptase (hTERT) could protect neonatal mitochondrial DNA (mtDNA) from oxidative damage during pregnancies complicated by gestational diabetes mellitus (GDM). METHODS 26 GDM mothers(More)
A transcription factor (TF) is a protein that binds to specific DNA sequences and thereby controls transcription. A large number of TFs are found in plants. The AP2/ERF family of TFs contain the AP2 DNA-binding domain, which play important roles in transcriptional regulation in plant life. To understand the AP2/ERF family TFs of maize, the discovery,(More)
Alzheimer's disease (AD), one of the most dreaded neurodegenerative disorders, is characterized by cortical and cerebrovascular amyloid β peptide (Aβ) deposits, neurofibrillary tangles, chronic inflammation, and neuronal loss. Increased bone fracture rates and reduced bone density are commonly observed in patients with AD, suggesting one or more common(More)
OBJECTIVES Accumulation of tissue advanced glycation end products (AGEs) is a marker of cumulative glycemic and/or oxidative stress. Cutaneous AGEs levels measured by skin autofluorescence correlate well with cardiovascular outcomes in diabetes and hemodialysis (HD) patients. The present study aimed to compare tissue AGEs levels with peritoneal dialysis(More)