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- Fei Liu, Justin D. Mih, +4 authors Daniel J Tschumperlin
- The Journal of cell biology
- 2010
Tissue stiffening is a hallmark of fibrotic disorders but has traditionally been regarded as an outcome of fibrosis, not a contributing factor to pathogenesis. In this study, we show that fibrosis… (More)
- Fei Liu, Emily Y Chu, +12 authors Sarah E. Millar
- Developmental biology
- 2008
Wnt/beta-catenin signaling plays key roles in tooth development, but how this pathway intersects with the complex interplay of signaling factors regulating dental morphogenesis has been unclear. We… (More)
- Khalid Iqbal, Alejandra del Carmen Alonso, +9 authors Inge Grundke-Iqbal
- Biochimica et biophysica acta
- 2005
Just as neuronal activity is essential to normal brain function, microtubule-associated protein tau appears to be critical to normal neuronal activity in the mammalian brain, especially in the… (More)
- Khalid Iqbal, Fei Liu, C L Gong, Alejandra del Carmen Alonso, Inge Grundke-Iqbal
- Acta Neuropathologica
- 2009
Alzheimer disease (AD) and related tauopathies are histopathologically characterized by a specific type of slow and progressive neurodegeneration, which involves the abnormal hyperphosphorylation of… (More)
- Fei Liu, Inge Grundke-Iqbal, Khalid Iqbal, Yoshiya Oda, Kazuhito Tomizawa, C L Gong
- The Journal of biological chemistry
- 2005
A disturbance of calcium homeostasis is believed to play an important role in the neurodegeneration of the brains of Alzheimer disease (AD) patients, but the molecular pathways by which it… (More)
- Fei Liu, Inge Grundke-Iqbal, Khalid Iqbal, C L Gong
- The European journal of neuroscience
- 2005
Abnormal hyperphosphorylation of tau is believed to lead to neurofibrillary degeneration in Alzheimer's disease (AD) and other tauopathies. Recent studies have shown that protein phosphatases (PPs)… (More)
- Thomas Andl, Elizabeth P. Murchison, +7 authors Sarah E. Millar
- Current Biology
- 2006
The discovery that microRNAs (miRNAs) play important roles in regulating gene expression via posttranscriptional repression has revealed a previously unsuspected mechanism controlling development and… (More)
The catalytic RNA subunit (M1 RNA) of RNase P from Escherichia coli has been converted to an endoribonuclease that specifically cleaves the mRNA that encodes thymidine kinase (TK) of herpes simplex… (More)
- L David Finger, Melvin Blanchard, +6 authors Binghui Shen
- The Journal of biological chemistry
- 2009
Flap endonuclease 1 (FEN1) proteins, which are present in all kingdoms of life, catalyze the sequence-independent hydrolysis of the bifurcated nucleic acid intermediates formed during DNA replication… (More)
- C.-X. Gong, Fei Liu, Inge Grundke-Iqbal, Khalid Iqbal
- Journal of Neural Transmission
- 2004
Microtubule-associated protein tau undergoes several post-translational modifications and aggregates into paired helical filaments (PHFs) in Alzheimer’s disease (AD) and other tauopathies. These… (More)