Fei Hou

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PURPOSE To investigate the impact of Pro370Leu mutant myocilin on endoplasmic reticulum (ER) stress response and mitochondria function in human trabecular meshwork (HTM) cells. METHODS HTM cells were transfected with wild-type Pro370Leu mutant myocilin or pcDNA3.1 (+) expression plasmids. The effect of the mutant myocilin on ER stress response was(More)
Real-time and realistic physics-based simulation of deformable objects is of great value to medical intervention, training, and planning in virtual environments. This paper advocates a virtual-reality (VR) approach to minimally-invasive surgery/therapy (e.g., percutaneous coronary intervention) in medical procedures. In particular, we devise a robust and(More)
This paper presents a novel modeling framework to build 3D models of Chinese architectures from elevation drawing. Our algorithm integrates the capability of automatic drawing recognition with powerful procedural modeling to extract production rules from elevation drawing. First, different from the previous symbol-based floor plan recognition, based on the(More)
This paper advocates a new component-aware framework to reconstruct 3D architecture from a single image. Different from existing work, our motivation is to obtain a complete set of semantically correct 3D architectural components, which enables part reusability towards rapid model reproduction and facilitates model variation. The core of our system is a(More)
PURPOSE Patients reproduce symptoms of primary open-angle glaucoma (POAG) when treated with glucocorticoids (GCs) topically on the eyes. Here we investigated the effects of GCs on junctional protein expression and cytoskeleton organization in primary human trabecular meshwork (TM) cultures to understand the molecular pathologies of POAG. METHODS Human TM(More)
BACKGROUND The existence of Tc17 cells was recently shown in several types of infectious and autoimmune diseases, but their distribution and functions in uterine cervical cancer (UCC) have not been fully elucidated. METHODS The frequency of Tc17 cells in peripheral blood samples obtained from UCC patients, cervical intraepithelial neoplasia (CIN) patients(More)
This paper presents Poisson vector graphics, an extension of the popular first-order diffusion curves, for generating smooth-shaded images. Armed with two new types of primitives, namely Poisson curves and Poisson regions, PVG can easily produce photorealistic effects such as specular highlights, core shadows, translucency and halos. Within the PVG(More)
In this paper, we present an efficient robust labeling method for coronary arteries from X-ray angiograms based on energy optimization. The fundamental goal of this research is to facilitate the analysis and diagnosis of interventional surgery in the most efficient way, and such effort could also improve the performance during doctor training, and surgery(More)