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Bioactive 7-Oxabicyclic[6.3.0]lactam and 12-Membered Macrolides from a Gorgonian-Derived Cladosporium sp. Fungus
One new bicyclic lactam, cladosporilactam A (1), and six known 12-membered macrolides (2–7) were isolated from a gorgonian-derived Cladosporium sp. fungus collected from the South China Sea. Their…
A new antiviral pregnane from a gorgonian-derived Cladosporium sp. fungus
- Mei-Lin Yu, Fei-Fei Guan, Fei Cao, Y. Jia, Chang-Yun Wang
- ChemistryNatural product research
- 1 June 2018
A new pregnane, 3α-hydroxy-7-ene-6,20-dione, and five known steroids, along with one known steroidal glycoside, were obtained from the fungus Cladosporium sp.
Aspergixanthones I–K, New Anti-Vibrio Prenylxanthones from the Marine-Derived Fungus Aspergillus sp. ZA-01
Aspergixanthone I (1) showed the strongest anti-Vibrio activity against Vibrio parahemolyticus, while three new prenylxanthone derivatives, asperGixanthones I–K (1–3), and four known analogues (4–7) were obtained.
Anti-Phytopathogenic and Cytotoxic Activities of Crude Extracts and Secondary Metabolites of Marine-Derived Fungi
- Dong-Lin Zhao, Dan Wang, Xueying Tian, Fei Cao, Yiqiang Li, Chengsheng Zhang
- Biology, ChemistryMarine drugs
- 1 January 2018
Evaluation of the anti-phytopathogenic bacterial and fungal activities, as well as the cytotoxicity of these 31 extracts, revealed that most of them displayed different levels of bioactivities.
Bioactive 3-Decalinoyltetramic Acids Derivatives From a Marine-Derived Strain of the Fungus Fusarium equiseti D39
All 3DTAs derivatives exhibited a potent phytotoxicity, and 5 displayed a remarkable anti-phytopathogenic activity superior to the positive control resulting in damage of the cell membrane of Pseudomonas syringae and ensuing leakage of the intracellular components.
Asperienes A–D, Bioactive Sesquiterpenes from the Marine-Derived Fungus Aspergillus flavus
This is the first time that two pairs of C-6′/C-7′ epimeric drimane sesquiterpene esters have successfully been separated and, Interestingly, compounds 1 and 4 exhibited lower toxicities than 2 and 3 toward normal GES-1 cells, indicating more potential for development as an antitumor agent in the future.
Bioactive Pregnane Steroids from a South China Sea Gorgonian Carijoa sp.
- Hong-Ying Zhao, C. Shao, Zhi-Yong Li, Lei Han, Fei Cao, Chang-Yun Wang
- Chemistry, BiologyMolecules
- 1 March 2013
A new pregnane steroid, 1, and three known analogues 2–4, have been isolated from a gorgonian Carijoa sp. collected from the South China Sea. The planar structure and relative configuration of 1 were…
Aspergoterpenins A–D: Four New Antimicrobial Bisabolane Sesquiterpenoid Derivatives from an Endophytic Fungus Aspergillus versicolor
Aspergoterpenins A–D (1–4), four new bisabolane sesquiterpenoid derivatives, were obtained from the endophytic fungus, Aspergillus versicolor, together with eight known compounds (5–12), and their…
Antibacterial Indole Alkaloids and Anthraquinones from a Sewage-Derived Fungus Eurotium sp.
- Dan Zhao, Fei Cao, Xiujie Guo, Yunlong Zhang, Zengjun Kang, Hua-Jie Zhu
- ChemistryChemistry of Natural Compounds
- 13 April 2018
Eurotium, a common fungus closely related to human life, is adapted to high osmotic pressure and can adapt to a low water environment . They are dominant microorganisms that are found during the…
Bastimolide B, an Antimalarial 24-Membered Marine Macrolide Possessing a tert-Butyl Group.
A methanolysis mechanism for bastimolide A is proposed, and one unexpected isomerization product of the C2-C3 double bond, 2-(E)-bastimolides A (3), was obtained.