Federico Pérez González

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The generation of induced pluripotent stem (iPS) cells has enabled the derivation of patient-specific pluripotent cells and provided valuable experimental platforms to model human disease. Patient-specific iPS cells are also thought to hold great therapeutic potential, although direct evidence for this is still lacking. Here we show that, on correction of(More)
The development of new gene-editing tools, in particular the CRISPR/Cas system, has greatly facilitated site-specific mutagenesis in human embryonic stem cells (hESCs), including the introduction or correction of patient-specific mutations for disease modeling. However, integration of a reporter gene into an endogenous locus in hESCs still requires a(More)
Coding at the sample level in still image watermarking takes advantage of avoiding a non-optimum initial diversity stage, used in many watermarking systems for tailoring Gaussian channels with desired properties. Nevertheless, the low signal to noise ratio (SNR) encountered, due to the perceptual constraints imposed to the watermark, makes necessary the use(More)
  • Juan Flores, Federico González, Beatriz Flores, Fac Ing, Fac Eléctrica, Contabilidad +1 other
  • 2008
We present a methodology to perform Financial Analysis with as much information as available. The problem we solve is the assessment of investment projects; we are to determine whether or not an investment project is profitable. We perform that task at the qualitative, semi-quantitative, and quantitative levels, depending on how much information there is at(More)
Experimental determination of the areas enclosed under the up curve, sigma = sigma(;gamma), corresponding to time zero, and the down curve, which would be obtained following complete rheodestruction of the system structure, is not an easy matter. In the present study a semi-empirical procedure for calculating the hypothetical values of these parameters is(More)
  • Jesús-Alejandro Peña-Jiménez, Federico González, Rigoberto López-Juárez, José-Manuel Hernández-Alcántara, Enrique Camarillo, Héctor Murrieta-Sánchez +2 others
  • 2016
The solid-state method was used to synthesize single phase potassium-sodium niobate (KNN) co-doped with the La 3+ –Mn 4+ and Eu 3+ –Fe 3+ ion pairs. Structural determination of all studied solid solutions was accomplished by XRD and Rietveld refinement method. Electron paramagnetic resonance (EPR) studies were performed to determine the oxidation state of(More)
The most frequent rearrangement of the human MLL gene fuses MLL to AF4 resulting in high-risk infant B-cell acute lymphoblastic leukemia (B-ALL). MLL fusions are also hallmark oncogenic events in secondary acute myeloid leukemia. They are a direct consequence of mis-repaired DNA double strand breaks (DNA-DSBs) due to defects in the DNA damage response(More)
A new method for low complexity image coding is presented, that permits different settings and great scalability in the generation of the final bit stream. This coding presents a continuous-tone still image compression system that groups loss and lossless compression making use of finite arithmetic reversible transforms. Both transformation in the space of(More)
The aim of this work is to continue with the ideas in Flores et al. [3] including the proposed greedy algorithm in order to develop them. When cash becomes available in a company, there are several strategies that allow us to benefit from it. The problem is how much to invest, for how long, and using which of the investment options in order to get the(More)
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