Federica Cattaneo

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Hematopoietic stem cell (HSC) gene therapy for adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID) has shown limited clinical efficacy because of the small proportion of engrafted genetically corrected HSCs. We describe an improved protocol for gene transfer into HSCs associated with nonmyeloablative conditioning. This protocol was(More)
A large proportion of Wiskott-Aldrich syndrome (WAS) patients develop autoimmunity and allergy. CD4(+)CD25(+)FOXP3(+) natural regulatory T (nTreg) cells play a key role in peripheral tolerance to prevent immune responses to self-antigens and allergens. Therefore, we investigated the effect of WAS protein (WASP) deficiency on the distribution and suppressor(More)
We discuss the applicability of the kinematic α-effect formalism at high magnetic Reynolds numbers. In this regime the underlying flow is likely to be a small-scale dynamo, leading to the exponential growth of fluctuations. Difficulties arise with both the actual calculation of the α coefficients and with its interpretation. We argue that although the(More)
(Received ?? and in revised form ??) We consider the kinematic dynamo problem for a velocity field consisting of a mixture of turbulence and coherent structures. For these flows the dynamo growth rate is determined by a competition between the large eddies that have large magnetic Reynolds number but long turnover times and the small eddies that have low(More)
(2010). Long-Term duloxetine treatment normalizes altered brain-derived neurotrophic factor expression in serotonin transporter knockout rats through the modulation of specific neurotrophin isoforms. (2012). Stress-induced changes of hippocampal NMDA receptors: modulation by duloxetine treatment. PlosOne, 7:e37916. (2013). Glucocorticoid receptor and FKBP5(More)
Astrophysical magnetic fields often display remarkable organization, despite being generated by dynamo action driven by turbulent flows at high conductivity. An example is the eleven-year solar cycle, which shows spatial coherence over the entire solar surface. The difficulty in understanding the emergence of this large-scale organization is that whereas at(More)
  • S T E V E, N M T O B I A S 1 A N D F A U S T O C A T T A N, S M Tobias, F Cattaneo, F A U S T O C A T T A N E O 1 A N D S T E V E, N M T O B I A S
  • 2008
The convective model equations ((??)-(??)) were integrated for a wide range of parameters ; with varying degrees of supercriticality (as measured by Ra) and rotation rates (as measured by T a). For all cases, whether rotating or non-rotating, the results were qualitatively similar and so we focus here on describing the results for one representative case,(More)
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