Federica Cattaneo

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Hematopoietic stem cell (HSC) gene therapy for adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID) has shown limited clinical efficacy because of the small proportion of engrafted genetically corrected HSCs. We describe an improved protocol for gene transfer into HSCs associated with nonmyeloablative conditioning. This protocol was(More)
A large proportion of Wiskott-Aldrich syndrome (WAS) patients develop autoimmunity and allergy. CD4(+)CD25(+)FOXP3(+) natural regulatory T (nTreg) cells play a key role in peripheral tolerance to prevent immune responses to self-antigens and allergens. Therefore, we investigated the effect of WAS protein (WASP) deficiency on the distribution and suppressor(More)
We report time-of-flight experiments on photonic-crystal waveguide structures using optical Kerr gating of a femtosecond white-light supercontinuum. These photonic-crystal structures, based on engineered silicon-nitride slab waveguides, possess broadband low-loss guiding properties, allowing the group velocity dispersion of optical pulses to be directly(More)
Many studies on soil organic carbon (SOC) sequestration in perennial biomass crops are available for Atlantic and continental environments of North Central Europe, while there is insufficient information for Southern Europe. Therefore, we assessed SOC turnover under Mediterranean climate, after a 9-year-old conversion from two annual crop systems,(More)
Aims. We study the changes in the properties of turbulence driven by the magnetorotational instability in a shearing box, as the computational domain size in the radial direction is varied relative to the height Methods. We perform 3D simulations in the shearing box approximation, with a net magnetic flux, and we consider computational domains with(More)
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