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Despite increasing evidence to suggest that microRNA (miR)-146a and miR-181b are involved in the regulation of immune responses and tumor progression, their roles in silicosis remain to be fully elucidated. Therefore, the present study examined the roles of miR‑146a and miR‑181b in inflammatory responses, and their effect on the expression of the tumor(More)
OBJECTIVES This study aims at exploring associations of general self-efficacy (GSE), workplace violence and doctors' work-related attitudes. MATERIAL AND METHODS In this study a cross-sectional survey design was applied. Questionnaires were administrated to 758 doctors working in 9 hospitals of Zhengzhou, Henan province, China, between June and October(More)
OBJECTIVE To investigate the factors for hydrocephalus secondary to severe traumatic brain injury after surgery, and to explore a new theory and guideline for clinical early prevention and treatment for hydrocephalus.
 METHODS The clinical data regarding 107 patients with severe traumatic brain injury, who were admitted to our hospital from June 2010 to(More)
OBJECTIVE To examine the impact of microRNA-146a (miR-146a) on pulmonary function and disease severity in silicosis patients. METHODS Twenty-nine silicosis patients and six observation subjects were recruited. MiR-146a expression level was detected by qRT-PCR, and pulmonary function was assessed with a spirometer. RESULTS MiR-146a expression level was(More)
Some experimental animal studies reported that vanadium had beneficial effects on blood total cholesterol (TC) and triglyceride (TG). However, the relationship between vanadium exposure and lipid, lipoprotein profiles in human subjects remains uncertain. This study aimed to compare the serum lipid and lipoprotein profiles of occupational vanadium exposed(More)
Background To identify differentially expressed miRNAs profiles in bronchoalveolar lavage fluid (BALF) from patients with silicosis and consider the potential contribution of miRNAs to silicosis.Methods miRNAs expression profiling were performed in the cell fraction of BALF samples obtained from 9 subjects (3 silicosis observation subjects, 3 stage I and(More)
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