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  • Fausto Roila, Jørn Herrstedt, +20 authors Deborah Warr
  • Medicine
  • Annals of oncology : official journal of the…
  • 2010 (First Publication: 1 May 2010)
  • Despite the relevant progress achieved in the last 20 years,vomiting and, especially, nausea, continue to be two of themost distressing side-effects of cancer chemotherapy. In the late1990s severalExpand
  • Paul J. Hesketh, Steven M. Grunberg, +11 authors Kevin J. Horgan
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2003 (First Publication: 15 November 2003)
  • PURPOSE In early clinical trials with patients receiving highly emetogenic chemotherapy, the neurokinin antagonist aprepitant significantly enhanced the efficacy of a standard antiemetic regimenExpand
  • Giuseppe Curigliano, Daniela Maria Cardinale, +7 authors Fausto Roila
  • Medicine
  • Annals of oncology : official journal of the…
  • 2012 (First Publication: 1 October 2012)
  • Cardiovascular (CV) toxicity is a potential short- or long-term complication of various anticancer therapies. Some drugs, such as anthracyclines or other biological agents, have been implicated inExpand
  • Steven M. Grunberg, Daniel Chua, +9 authors Jørn Herrstedt
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2011 (First Publication: 10 April 2011)
  • PURPOSE Addition of aprepitant, a neurokinin-1 receptor antagonist (NK1RA), to an ondansetron and dexamethasone regimen improves prevention of chemotherapy-induced nausea/vomiting (CINV),Expand
  • Matti Aapro, Alexander Molassiotis, +8 authors Fausto Roila
  • Medicine
  • Annals of oncology : official journal of the…
  • 2012 (First Publication: 1 August 2012)
  • BACKGROUND While guidelines for preventing chemotherapy-induced nausea and vomiting (CINV) are widely available, clinical uptake of guidelines remains low. Our objective was to evaluate the effect ofExpand