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OBJECTIVES The purpose of this study was to evaluate the incidence, risk factors, indications, outcomes, and complications of emergency hysterectomy performed after cesarean deliveries (cesarean hysterectomy) and vaginal deliveries (postpartum hysterectomy). STUDY DESIGN We conducted a retrospective cohort study from 1990 to 2002 of patients who had(More)
BACKGROUND We evaluated clinical toxicity in HIV-infected persons receiving antiretroviral therapy (ART) in Uganda. METHODS From May 2003 through December 2004, adults with a CD4 cell count < or =250 cells/microL or World Health Organization stage 3/4 HIV disease were prescribed ART. We calculated probabilities for time to toxicity and single-drug(More)
OBJECTIVE To assess the effects of prophylactic misoprostol use in the third stage of labor compared with injectable uterotonics or placebo or no treatment. DATA SOURCES The Cochrane Pregnancy and Childbirth Group trials register; the Cochrane Library, including databases such as the database of systematic reviews and the Cochrane Controlled Trials(More)
BACKGROUND Around 120 million women worldwide suffer from Trichomonas vaginalis vaginitis every year. The infection is sexually transmitted and is believed to facilitate HIV transmission. OBJECTIVES To assess the effects of various treatment strategies for trichomoniasis in women. SEARCH STRATEGY We searched the Cochrane Central Register of Controlled(More)
Daily prophylaxis with trimethoprim-sulfamethoxazole (TMP-SMZ) significantly decreases morbidity and mortality among people living with HIV. Some clinicians are reluctant to use TMP-SMZ in pregnant and breastfeeding HIV-infected women because of concerns about the possible teratogenicity when used in the first trimester and about its potential to induce(More)
BACKGROUND Incomplete abortion is a major problem that should be effectively managed with safe and appropriate procedures. Surgical evacuation of the uterus for management of incomplete abortion usually involves vacuum aspiration or sharp curettage. OBJECTIVES To compare the safety and effectiveness of surgical uterine evacuation methods for management of(More)
OBJECTIVES To compare pregnancy outcomes between foreign-born women and women born in the United States (US-born). METHODS A retrospective cohort study (1991-2001) of all deliveries at Grady Memorial Hospital in Atlanta, Georgia. RESULTS Among 49,904 deliveries, 27% were to foreign-born mothers representing 164 countries grouped into eight geographic(More)
Prevention of mother-to-child human immunodeficiency virus (HIV) transmission (PMTCT) programs have nearly eliminated mother-to-child transmission of HIV in developed countries, but progress in resource-limited countries has been slow. A key factor limiting the scale-up of PMTCT programs is lack of knowledge of HIV serostatus. Increasing the availability(More)
BACKGROUND The authors evaluated hematologic changes associated with zidovudine (ZDV) following single-drug substitution from stavudine (D4T) in HIV-infected persons in Uganda. METHODS From May 2003 through February 2007, the authors evaluated incidence rates (IR) of hematologic abnormalities from quarterly blood draws among adults prescribed highly(More)
OBJECTIVE To identify social, behavioral and epidemiologic factors associated with HIV infection among HIV-infected and HIV-uninfected black women residing in North Carolina. DESIGN A case-control study conducted in August 2004 in North Carolina. METHODS Cases were 18-40-year-old women with HIV infections diagnosed from 2003-2004. Controls were(More)
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