A new antioxidant stilbene and other constituents from the stem bark of Morus nigra L.
- Ghada M. Abbas, Fatma M. Abdel Bar, H. N. Baraka, A. Gohar, M. Lahloub
- Chemistry, MedicineNatural Product Research
- 30 June 2014
The new stilbene exhibited remarkable antioxidant capacity with IC50 of 4.69 μM and was evaluated for their potential antioxidant activity using 2,2′-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid)+ radical-scavenging capacity assay and compared with ascorbic acid.
Antiproliferative triterpenes from Melaleuca ericifolia.
- Fatma M. Abdel Bar, A. Zaghloul, Sunitha V. Bachawal, P. Sylvester, Kadria F. Ahmad, K. E. El Sayed
- ChemistryJournal of Natural Products
- 1 October 2008
Three new 28-norlupane triterpenes were isolated from the leaves of Melaleuca ericifolia and evaluated for antiproliferative activity against the malignant +SA mammary epithelial cell line.
Design and pharmacophore modeling of biaryl methyl eugenol analogs as breast cancer invasion inhibitors.
- Fatma M. Abdel Bar, M. Khanfar, K. E. El Sayed
- Biology, ChemistryBioorganic & Medicinal Chemistry
- 15 January 2010
Rational design and synthesis of topoisomerase I and II inhibitors based on oleanolic acid moiety for new anti-cancer drugs.
- A. Ashour, S. El-Sharkawy, K. Shimizu
- ChemistryBioorganic & Medicinal Chemistry
- 2014
Antioxidants and α-Glucosidase Inhibitors from Lactuca serriola L.
- Nouran H. Abdel Fatah, Yhiya Amen, Fatma M. Abdel Bar, A. Halim, H. A. Saad
- Chemistry
- 27 July 2020
Our main objective in the present study was investigation of potential antidiabetic and antioxidant compounds from the methanol extract of Lactuca serriola L. Phytochemical investigation allowed the…
Synthesis of new selective cytotoxic ricinine analogues against oral squamous cell carcinoma
- M. H. El-naggar, Fatma M. Abdel Bar, F. Badria
- Chemistry, BiologyNatural Product Research
- 17 September 2019
Ricinine analogue (19) was shown to be the most active derivative and showed downregulation of COX-2 which is also extensively expressed in oral cancer, and PTP1B was predicted to be a target for ricinine using reverse docking approach.
Synthesis, docking, cytotoxicity, and LTA4H inhibitory activity of new gingerol derivatives as potential colorectal cancer therapy.
- M. H. El-naggar, Amira Mira, Fatma M. Abdel Bar, K. Shimizu, M. Amer, F. Badria
- Chemistry, BiologyBioorganic & Medicinal Chemistry
- 1 February 2017
Antimicrobial and antiquorum-sensing activity of Ricinus communis extracts and ricinine derivatives
- M. H. El-naggar, A. Elgaml, Fatma M. Abdel Bar, F. Badria
- Chemistry, BiologyNatural Product Research
- 1 June 2019
Findings proved the usefulness of ricinine as a good scaffold for the synthesis of new antimicrobial and antiquorum-sensing derivatives in spite of its poor contribution to the antimicrobial activity of the plant extracts.
Quorum Sensing Inhibiting Activity of Streptomyces coelicoflavus Isolated from Soil
- R. Hassan, Mona I. Shaaban, Fatma M. Abdel Bar, Areej M El-Mahdy, S. Shokralla
- BiologyFrontiers in Microbiology
- 13 May 2016
Quorum sensing (QS) systems communicate bacterial population and stimulate microbial pathogenesis through signaling molecules. Inhibition of QS signals potentially suppresses microbial infections.…
Treatment of Vinca minor Leaves with Methyl Jasmonate Extensively Alters the Pattern and Composition of Indole Alkaloids.
- Sara Abouzeid, U. Beutling, D. Selmar
- ChemistryJournal of Natural Products
- 13 November 2017
It is postulated that vincamine is a precursor of 9-methoxyvincamine, which represents a novel natural product in V. minor and could be used as a potential elicitor of alkaloids that are not produced under normal conditions.
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