Fatma Kurtuluş

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Aim. To asses both choroidal thickness differences among Alzheimer's type dementia (ATD) patients, mild cognitive impairment (MCI) patients, and healthy control (C) subjects and choroidal thickness relationships with cognitive performance. Methods. A total of 246 eyes of 123 people (41 ATD, 38 MCI, and 44 healthy C subjects) were included in this study.(More)
INTRODUCTION Oligodendrocytes need iron in processes of energy generation and myelination. However, excessive levels of iron may exert iron induced oxidative stress and thus lead to tissue degeneration. Monitoring oxidative stress will be of paramount importance in follow-up of patients with many diseases including multiple sclerosis (MS). The aim of this(More)
The impact and pathogenesis of iron accumulation in multiple sclerosis (MS) is not yet clear. In this study, we investigated serum markers of iron metabolism, namely iron, ferritin, transferrin, total iron binding capacity (TIBC), and hepcidin in patients with MS, and compared to a healthy control group. Thirty-five stable relapse remitting MS patients (15(More)
PURPOSE To assess cognitive performance differences among primary open-angle glaucoma (POAG) patients, normal-tension glaucoma (NTG) patients, and healthy control (C) subjects. METHODS A total of 60 participants (20 POAG, 20 NTG, and 20 C subjects) were included in this study. A detailed ophthalmologic examination was performed on all participants. A(More)
As anti-oxidative therapies come into consideration, finding feasible markers of oxidative stress becomes mandatory. We here in this study investigated the levels of major internal antioxidant uric acid (UA), oxidative stress parameters total antioxidant status (TAS), total oxidative status (TOS) in multiple sclerosis (MS) patients compared to controls.(More)
We would like to thank Ilhan et al. [1] for their comments regarding our article. In our study, we found out that choroidal thickness (CT) decreased in the eyes of patients with both Alzheimer’s type dementia (ATD) and mild cognitive impairment (MCI) compared to the healthy control group.Therefore, we suggested that CT value could be used as a new biomarker(More)
BACKGROUND/AIMS To identify the retinal vascular pathologies in patients with Alzheimer's type dementia (ATD) through optical coherence tomography angiography (OCTA) imaging. METHODS Our study included 26 patients in the patient group, and age-matched and sex-matched 26 subjects in the control group. A detailed ophthalmological and neurological(More)
BACKGROUND The klotho (Klt)-fibroblast growth factor-23 (FGF-23)-vitamin D axis is the main component of calcium (Ca) and phosphorus (P) metabolisms; on the contrary, it is also secreted from the choroid plexus (CP). PURPOSE This study is aimed at evaluating serum soluble Klt (sKlt), FGF-23, and 25-(OH)-vitamin D levels in multiple sclerosis (MS)(More)
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