Fati Nourhashemi

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BACKGROUND Patients with Alzheimer's disease (AD), even in the presence of symptomatic relief from medical intervention, face a persistent worsening of cognitive decline and performance in activities of daily living. Data regarding the long-term disease progression outside of therapeutic trials are lacking. We examined the effects of standard of care for AD(More)
BACKGROUND Patients with Alzheimer's disease (AD) commonly develop aversive feeding behaviours. These behaviours lead to weight loss and frequently to physicians using tube feeding. Little is known about factors correlated with feeding difficulties during AD. OBJECTIVE To investigate predictors of aversive feeding behaviours (AFBs) which occurred during a(More)
BACKGROUND There are presently no published data on age-related changes in body composition in French individuals older than 65 or 80 years. This paper presents a cross-sectional study of 7518 community-residing French women older than 75 years. METHODS We examined age differences changes in body composition and anthropometry between age groups (76-80,(More)
Information is lacking regarding the comparison of bone mineral and body composition measurements obtained from the different dual energy X-ray absorptiometry (DXA) systems. The purpose of this study is to compare body composition and whole body bone mineral density (BMD) measurements from the hologic QDR-4500 W (DXA H) and the lunar (DXA L) systems. Seven(More)
Missing data are frequent in Alzheimer's disease (AD) trials due to the age of participants and the nature of the disease. This can lead to bias and decreased statistical power. We assessed the level and causes of missing data in a 2-year randomised trial of an AD patient management program (PLASA study), and conducted sensitivity analyses on the primary(More)
OBJECTIVE To test the effectiveness of a comprehensive specific care plan in decreasing the rate of functional decline in patients with mild to moderate Alzheimer's disease compared with usual care in memory clinics. DESIGN Cluster randomised trial. SETTING 50 memory clinics in France. PARTICIPANTS Patients with Alzheimer's disease (mini-mental state(More)
OBJECTIVE To evaluate the frequency of and determine predictive factors for acute hospitalization in a prospective study of patients with Alzheimer's disease (AD). DESIGN A one year prospective study. PARTICIPANTS 134 patients recruited from the memory clinic in Toulouse University Hospital, with AD diagnosed using the NINCDS-ADRDA criteria. MEASURES(More)
Among elderly without cognitive impairment, poor physical performances have been reported to predict cognitive decline and dementia. Our aim was to explore the predictive value of balance impairment for cognitive decline in 686 community-dwelling Alzheimer's disease (AD) patients (REAL.FR study). Being unable to stand on one leg for five seconds or more(More)
BACKGROUND Attrition, i.e. patient dropout, can threaten the validity of results in longitudinal studies. The aim of this study was to identify patient and caregiver factors predictive of attrition in a cohort of Alzheimer disease (AD) patients. METHODS 686 patients with mild to moderate AD were included in the multicenter prospective REAL.FR study.(More)
OBJECTIVE To describe the cognitive, functional, and nutritional features of patients admitted to a Special Acute Care Unit (SACU) for elderly patients with Alzheimer's disease (AD). METHODS One-year observational study of patients with AD and other related disorders hospitalized in the SACU, Department of Geriatrics, Toulouse university Hospital during(More)