Faten Zahran Mohamed

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Recent studies have identified several single nucleotide polymorphisms (SNPs) in the population that are associated with variations in the risks of many different cancer diseases. For ovarian cancer, the known highly penetrant susceptibility genes (BRCA1 and BRCA2) are probably responsible for only 40 % of the excess familial ovarian cancer risks,(More)
Hepatocellular carcinoma (HCC) is a worldwide neoplasm for which early diagnosis is difficult and the prognosis is usually poor. Overexpression of cyclooxygenase 2 (COX-2) has been suggested to be associated with hepatocarcinogenesis. Although several COX-2 inhibitors have been used in hepatoma therapy, the genetic background between COX-2 and HCC remains(More)
Cytokines play a main role as progressive factors in nephrotic syndrome (NS). Tumor necrosis factor alpha (TNFα) produced by activated macrophages is often accompanied by pro inflammatory properties. Some cytokine gene polymorphisms like TNFα have associated with various inflammatory diseases as glomerulonephritis. The aim of the current work was to(More)
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