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Journals and Conferences
Hemoglobin is the major protein in red blood cells and transports oxygen from the lungs to oxygen-demanding tissues, like the brain. Mechanisms that facilitate the uptake of oxygen in the vertebrate brain are unknown. In invertebrates, neuronal hemoglobin serves as intracellular storage molecule for oxygen. Here, we show by immunohistochemistry that… (More)
On the basis of its inhibition by SB216763, we identified the multifunctional enzyme Glycogen Synthase Kinase 3beta (GSK3beta) as a central regulator for differentiation and cell survival of adult neural stem cells. Detected by proteomic approaches, members of the Wnt/beta-catenin signaling pathway appear to participate in enhanced neuronal differentiation… (More)
A bipolar ADSL line driver for central office achieves 75dB MTPR. Employing a single-active-termination topology, it has 710mW total dissipation including 20.4dBm delivered to the line. Class-AB biasing makes the 4mA quiescent current independent of process, temperature, and supply variations.