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OBJECT The authors describe a computer-resident digital representation of a stereotactic atlas of the human brainstem, its semiautomated registration to sagittal fast low-angle shot three-dimensional (3-D) magnetic resonance (MR) imaging data sets in 27 healthy volunteers and 24 neurosurgical patients, and an analysis of the subsequent transforms needed to(More)
OBJECTIVE This is a retrospective analysis of 25 consecutive pediatric patients with Cushing's disease who underwent transsphenoidal surgery performed by a single neurosurgeon in a specialist center during a 20-year period. This article discusses the presentation of Cushing's disease, the endocrinological investigation with particular reference to bilateral(More)
Thirty craniopharyngiomas were operated on between 1983 and 1993. Eight patients underwent surgery solely via the transsphenoidal route. None of these had undergone surgery previously. The eight patients were followed up for a period of 120 months (mean 87.5 months). The tumour was removed totally in five and subtotally in three patients. All eight patients(More)
The authors present a case of an intraventricular 14-cm fetus in a 6-week-old infant who presented with enlarging head size. The entire intracranial fetus, with recognizable limbs, trunk, head, and exomphalos, was removed totally from the lateral and third ventricles, with excellent recovery in the patient, who is now 18 months old. The cytogenetical and(More)
An investigation was made of the use of a new water-soluble contrast material (metrizamide) for posterior-fossa radiography in the baboon. The experiments showed that the concentration of metrizamide needed to produce adequate radiographs from sub-occipital injections into the posterior fossa always produced generalized seizures. Intraventricular injection(More)
The spatial configuration of the trigeminal nuclear complex has been determined using new computer techniques aided by color graphic display facilities. Precise, statistical computer-generated drawings are provided of the three-dimensional anatomy of the nuclear complex and spinal tract of the fifth cranial nerve, as well as adjacent structures. Techniques(More)