Farrukh Naveed

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Low plasma busulfan (Bu) area under the concentration-time curve (AUC) is associated with graft failure and relapsed leukemias, and high AUC with toxicities when Bu is used orally or i.v. 4 times daily combined with cyclophosphamide in myeloablative hematopoietic stem cell transplantation (SCT) conditioning regimens. We report Bu AUC and its association(More)
Intravenous (i.v.) busulfan (Bu) administered once daily in myeloablative transplant regimens is convenient, effective, and relatively well tolerated. Therapeutic drug monitoring is recommended as nonrelapse mortality increases when daily exposure, as determined by the area under the plasma concentration versus time curve (AUC), exceeds 6000 μM·min. We(More)
In recent years there has been a rapidly increasing intensity of work going into investigating various methods of facilitating assisted living for the benefit of the elderly and those with difficulties in mobility. The paper describes one such effort which distinguishes itself from the rest by considering and describing a system with true commercial(More)
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