Farhid Farahmandghavi

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In this study, oregano essential oil (OEO) has been encapsulated in chitosan nanoparticles by a two-step method, i.e., oil-in-water emulsion and ionic gelation of chitosan with sodium tripolyphosphate (TPP). The success of OEO encapsulation was confirmed by Fourier transform infrared (FT-IR) spectroscopy, UV-vis spectrophotometry, thermogravimetric analysis(More)
The objective of this work was to develop active bio-based nanocomposite films from fish gelatin (FG) and chitosan nanoparticles (CSNPs) incorporated with Origanum vulgare L. essential oil (OEO). CSNPs were obtained by ionic gelation of chitosan with sodium tripolyphosphate, which presented a spherical morphology with size range of 40-80nm. Remarkable(More)
Nowadays, there is a lot of interest in developing long-acting drug delivery devices for human or veterinary applications including monolithic systems. Drug content uniformity of a monolithic device is highly dependent on the uniform distribution of drug particles within the polymeric matrix both in dispersion and distribution levels. Here, a range of(More)
OBJECTIVES Over the past few decades, mathematical modelling and simulation of drug delivery systems has been steadily gained interest as a focus for academic and industrial attention. Here, simulation of dexamethasone (DEX, a corticosteroid anti-inflammatory agent) release profile from drug-eluting cochlear implant coatings is reported using artificial(More)
OBJECTIVES The coating of cochlear implants for topical delivery of drugs, for example, corticosteroids, or antibiotics is a novel approach to manage post-surgical complications associated with cochlear implantation surgery like inflammation or infections. Many variables, including formulation parameters, can be changed to modulate the amount and duration(More)
Silicone rubbers are widely used as carriers for delivery of drugs intended for parenteral administration as implantable devices. Drugs having different functional groups can significantly affect curing profile of silicone rubber, which in turn may negatively affect their biological applicability due to the loss in mechanical and drug retaining properties.(More)
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