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Voriconazole Exposure and Risk of Cutaneous Squamous Cell Carcinoma, Aspergillus Colonization, Invasive Aspergillosis and Death in Lung Transplant Recipients.

• Matthew D Mansh, Maxwell Binstock, +11 authors Sarah T Arron
• American journal of transplantation : official…
• 2016

Voriconazole is a triazole antifungal used to prevent and treat invasive fungal infections after lung transplantation, but it has been associated with an increased risk of developing cutaneous… (More)

Occlusion effect on in vivo percutaneous penetration of chemicals in man and monkey: partition coefficient effects.

• Farhaan Hafeez, Howard Maibach
• Skin pharmacology and physiology
• 2013

BACKGROUND/AIM Skin occlusion can increase the hydration of the stratum corneum up to 50%, which can have substantial effects on the percutaneous absorption of penetrants by altering skin barrier… (More)

Ciclopirox delivery into the human nail plate using novel lipid diffusion enhancers.

• Farhaan Hafeez, Xiaoying Hui, Marc Selner, Bert Rosenthal, Howard Maibach
• Drug development and industrial pharmacy
• 2014

CONTEXT Onychomycosis is a common fungal infection of the nail plate and bed that affects up to 14% of the population and can have a substantial impact on the quality of life of those affected. … (More)

Skin lesion metrics: role of photography in acne.

• Audris Chiang, Farhaan Hafeez, Howard Ira Maibach
• The Journal of dermatological treatment
• 2014

Accurate assessment of acne severity is essential for determining the appropriate treatment required. This paper reviews photographic methods for such assessment. Literature included met the… (More)

Stratum corneum reservoir as a predictive method for in vitro percutaneous absorption.

• Farhaan Hafeez, Audris Chiang, Xiaoying Hui, Hanjiang Zhu, Faraz Kamili, Howard Ira Maibach
• Journal of applied toxicology : JAT
• 2016

Interaction between drug and proteins and lipids in stratum corneum (SC) is an important pharmacokinetic parameter in early steps of absorption. Previous in vivo studies showed that the total amount… (More)

Role of partition coefficients in determining the percutaneous penetration of salicylic acid and formaldehyde under varying occlusion durations.

• Farhaan Hafeez, Audris Chiang, Xiaoying Hui, Howard Ira Maibach
• Drug development and industrial pharmacy
• 2014

CONTEXT Occlusion is widely utilized to enhance the percutaneous penetration of applied drugs in clinical practice; however, occlusion does not increase the penetration of all chemicals. OBJECTIVE… (More)

An overview of parabens and allergic contact dermatitis.

• Farhaan Hafeez, Howard Maibach
• Skin therapy letter
• 2013

Esters of p-hydroxybenzoic acid (parabens) are the most widely used preservatives in cosmetic, pharmaceutical, and industrial products. However, since the 1960s, controversy has surrounded its use… (More)

Do partition coefficients (liphophilicity/hydrophilicity) predict effects of occlusion on percutaneous penetration in vitro: a retrospective review.

• Farhaan Hafeez, Howard Maibach
• Cutaneous and ocular toxicology
• 2013

CONTEXT Skin occlusion influences percutaneous penetration by limiting penetrant evaporation, but also through impeding loss of water from skin and increasing the hydration state of the stratum… (More)

Dermal exposure to methamphetamine hydrochloride contaminated residential surfaces II. Skin surface contact and dermal transfer relationship.

• Charles B Salocks, Xiaoying Hui, +4 authors Howard Ira Maibach
• Food and chemical toxicology : an international…
• 2014

This in vitro investigation evaluated [(14)C] - d-methamphetamine hydrochloride ([(14)C]-meth HCl) transfer from contaminated vinyl tile (non-porous and smooth) and upholstery fabric (rough and… (More)

Transungual delivery of ketoconazole using novel lacquer formulation.

• Farhaan Hafeez, Xiaoying Hui, Audris Chiang, Sidney Hornby, Howard Ira Maibach
• International journal of pharmaceutics
• 2013

Onychomycosis, a common fungal infection of the nail, can have a substantial impact on quality of life. The success of topical therapy for onychomycosis depends on effective penetration, which can be… (More)

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