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Cardiovascular disease remains the leading cause of mortality in westernized countries, despite optimum medical therapy to reduce the levels of low-density lipoprotein (LDL)-associated cholesterol. The pursuit of novel therapies to target the residual risk has focused on raising the levels of high-density lipoprotein (HDL)-associated cholesterol in order to(More)
Introduction: Designer Cannabinoids is a newly emerging drug of abuse that gained popularity among adolescent and young adults in the past few years. These drugs are marketed as incense or potpourri under different brand names such as spice. The potency of these drugs is variable and the range of adverse effects range from simple to severe and life(More)
Study design: A case report of Spinal myoclonus. Objectives: To illustrate an unusual case of spinal myoclonus and its management. Case report: A 48 year old male was admitted with minor trauma to his lower back for which he needed epidural analgesia. He later developed focal myoclonus of the left lower limb. He was subsequently investigated and treated(More)
Ebstein anomaly is characterized by deformities of the anterior leaflet of the tricuspid valve and atrialization of the right ventricle. Patients with severe tricuspid regurgitation are recommended to have tricuspid valve surgery with concomitant atrial septal defect closure. A 73-year-old female with Ebstein anomaly presented with severe hypoxemia.(More)
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.46 0.0041 RGS5 regulator of G-protein signaling 5 1.36 0.0297 SLC22A23 solute carrier family 22, member 23 1.29 0.0069 C1orf158 chromosome 1 open reading frame 158 1.28 0.0044 PIN4 (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) 1.27 0.0006 FLT1 fms-related tyrosine kinase 1(More)
Cardiovascular disease (CVD) remains the leading cause of mortality in westernized countries, despite optimum medical therapy to lower LDL cholesterol. The pursuit of novel therapies to target this residual risk has focused on raising levels of HDL cholesterol in order to exploit its atheroprotective effects 1. MicroRNAs have emerged as important(More)
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