Farah Abdul-Rahman

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Bacterial microcompartments (BMCs) are proteinaceous organelles that carry out specific metabolic reactions. Using domain representations of the BMC shell proteins, we identified BMCs in genomes of 358 bacterial species including human gut microbes, bioremediation agents, cellulosic ethanol producers, and pathogens. Multiple BMCs of different metabolic(More)
Direct cell programming via overexpression of transcription factors (TFs) aims to control cell fate with the degree of precision needed for clinical applications. However, the regulatory steps involved in successful terminal cell fate programming remain obscure. We have investigated the underlying mechanisms by looking at gene expression, chromatin states,(More)
Cell growth rate is regulated in response to the abundance and molecular form of essential nutrients. InSaccharomyces cerevisiae(budding yeast), the molecular form of environmental nitrogen is a major determinant of cell growth rate, supporting growth rates that vary at least threefold. Transcriptional control of nitrogen use is mediated in large part by(More)
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