Fangfang Yang

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Tamoxifen is widely used to treat hormone-dependent breast cancer, but its therapeutic benefit is limited by the development of drug resistance. Here, we investigated the role of estrogen G-protein coupled receptor 30 (GPR30) on Tamoxifen resistance in breast cancer. Primary tumors (PTs) of breast cancer and corresponding metastases (MTs) were used to(More)
A novel method using ethanol was proposed for extracting lipids from wet microalga Picochlorum sp. at room temperature and pressure. In this study, Central Composite design (CCD) was applied to investigate the optimum conditions of lipid extraction. The results revealed that the solvent to biomass ratio had the largest effect on lipid extraction efficiency,(More)
A laboratory study was conducted on biomass and lipid production by Scenedesmus sp. and the removal of total nitrogen (TN) and total phosphorus (TP) from filtered anaerobically digested piggery wastewater. The dry weight (DW), lipid content and productivity, total nitrogen, and total phosphorus removal rate were assessed in five media: modified soil extract(More)
Breast carcinoma is the most common female cancer with considerable metastatic potential. Signal transducers and activators of the transcription 3 (Stat3) signaling pathway is constitutively activated in many cancers including breast cancer and has been validated as a novel potential anticancer target. Here, we reported our finding with nifuroxazide, an(More)
BACKGROUND Natural forest succession often affects soil physical and chemical properties. Selected physical and chemical soil properties were studied in an old-growth forest across a forest successional series in Dinghushan Nature Reserve, Southern China. METHODOLOGY/PRINCIPAL FINDINGS The aim was to assess the effects of forest succession change on soil(More)
Lipid production is an important indicator for assessing microalgal species for biodiesel production. In this work, the effects of medium composition on lipid production by Scenedesmus sp. were investigated using the response surface methodology. The results of a Plackett-Burman design experiment revealed that NaHCO₃, NaH₂PO4·2H₂O and NaNO₃ were three(More)
The emergence of numerous nanoscale materials and structures such as nanowires (NWs), nanorods, nanotubes, and nanobelts of various materials in the past decade has prompted a need for methods to characterize their unique mechanical properties. These one-dimensional (1D) nanostructures possess superior mechanical properties [1, 2]; hence, applications of(More)
Melanoma is a highly malignant neoplasm of melanocytes with considerable metastatic potential and drug resistance, explaining the need for new candidates that inhibit tumor growth and metastasis. The signal transducer and activator of the transcription 3 (Stat3) signaling pathway plays an important role in melanoma and has been validated as promising(More)