Fang Rong Hsu

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UNLABELLED In the past years, identification of alternative splicing (AS) variants has been gaining momentum. We developed AVATAR, a database for documenting AS using 5,469,433 human EST sequences and 26,159 human mRNA sequences. AVATAR contains 12000 alternative splicing sites identified by mapping ESTs and mRNAs with the whole human genome sequence.(More)
Among 75218 splicing sites, 137 colon cancer specific alternative splicing isoforms were found by mining EST database. Alternative splicing database were first constructed by aligning EST to genomic sequence. Numbers of ESTs from normal or cancer colon tissue supporting splicing isoform at each splicing site were then queried and analyzed with Fisher exact(More)
Expressed sequence tags (ESTs) are single-pass sequence reads from cDNA clones. ESTs usually represent genes expressed in a particular tissue. Single nucleotide polymorphism (SNP) is a very important resource for protein structure and function. It may make a contribution to understand a complex disease, such as tumor. Through analysis of large scale human(More)
In this paper, we propose an algorithm for hiding (DNA Deoxyribonucleic acid) sequence in H.264/AVC video. The DNA sequence is first encrypted by a rule before hiding, and then we embed encrypted DNA sequence into the quantized discrete cosine transform (QDCT) coefficients of the 4x4 macroblocks (MBs) of Intra-frames (I-frames). To avert the distortion(More)
ESTs usually are used for genes expression in a particular organ, tissue. Genetic variations may make a contribution to understand a complex disease, such as cancer. SNP is a very important resource for protein structure and function. We are interested about the relationship between SNPs and tumors in humans. In the study, bioinformatics methods are used to(More)
As a great number of the genomic DNA sequences can now be generated in a day, the demand for a very fast and accurate method for positioning genomic DNA sequences on a genome is high. A unique marker is a sequence which appears only once in a genome. The unique marker method is an efficient method to perform this task. The amount of time needed for(More)
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