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- Fan Zhang, Qiang Fan, Keqin Ren, Paul R. Andreassen
- Molecular cancer research : MCR
- 2009
BRCA1 and BRCA2 are prominently associated with inherited breast and ovarian cancer. The encoded proteins function in DNA damage responses, but no functional link between BRCA1 and BRCA2 has been… (More)
- Fan Zhang, Guo Yong Zhang, Andrew Y. Zhang, Matthew J. Koeberl, Eryn Wallander, P L Li
- American journal of physiology. Heart and…
- 2006
The present study was designed to determine the production of nicotinic acid adenine dinucleotide phosphate (NAADP) and its role associated with lysosomes in mediating endothelin-1 (ET-1)-induced… (More)
- Sergey V Brodsky, Fan Zhang, Alberto Nasjletti, Michael S. Goligorsky
- American journal of physiology. Heart and…
- 2004
Endothelial cell dysfunction (ECD) is emerging as the common denominator for diverse and highly prevalent cardiovascular diseases. Recently, an increased number of procoagulant circulating… (More)
- Marco Seandel, Jason M. Butler, +11 authors Shahin Rafii
- Proceedings of the National Academy of Sciences…
- 2008
Vascular cells contribute to organogenesis and tumorigenesis by producing unknown factors. Primary endothelial cells (PECs) provide an instructive platform for identifying factors that support stem… (More)
- Francesca Aguiló, Fan Zhang, +15 authors Martin J. Walsh
- Cell stem cell
- 2015
Epigenetic and epitranscriptomic networks have important functions in maintaining the pluripotency of embryonic stem cells (ESCs) and somatic cell reprogramming. However, the mechanisms integrating… (More)
- Xu Wei Hou, Anil Kumar, +19 authors Xuri Li
- Proceedings of the National Academy of Sciences…
- 2010
The importance of identifying VEGF-independent pathways in pathological angiogenesis is increasingly recognized as a result of the emerging drug resistance to anti-VEGF therapies. PDGF-CC is the… (More)
- Zheng Dong Liang, Yan Long, +9 authors Marcus Tien Kuo
- Molecular cancer therapeutics
- 2012
Platinum-based antitumor agents are widely used in cancer chemotherapy. Drug resistance is a major obstacle to the successful use of these agents because once drug resistance develops, other… (More)
- Zan Pan, Zheng Wang, Hua Yang, Fan Zhang, Peter Sol Reinach
- Investigative ophthalmology & visual science
- 2011
PURPOSE
To determine whether hypertonic stress promotes increases in inflammatory cytokine release through transient receptor potential vanilloid channel type 1 (TRPV1) signaling pathway activation… (More)
The present study was designed to determine whether the sarcoplasmic reticulum (SR) could locally produce superoxide (O2-) via NAD(P)H oxidase (NOX) in coronary arterial myocytes (CAMs) and to… (More)
- Atsuko Sakurai, Julie Gavard, +9 authors J. Silvio Gutkind
- Molecular and cellular biology
- 2010
Recent studies revealed that a class III semaphorin, semaphorin 3E (Sema3E), acts through a single-pass transmembrane receptor, plexin D1, to provide a repulsive cue for plexin D1-expressing… (More)