Fan Yang

Publications209
h-index31
Citations4,396
Highly Influential Citations107
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The molecular structure of green fluorescent protein
TLDR
The crystal structure of recombinant wild-type green fluorescent protein (GFP) has been solved to a resolution of 1.9 Å by multiwavelength anomalous dispersion phasing methods and the identification of the dimer contacts may allow mutagenic control of the state of assembly of the protein. Expand
The Interfacial Behavior between Biochar and Soil Minerals and Its Effect on Biochar Stability.
TLDR
Results indicated that mineral-rich soils seemed to be a beneficial environment for biochar since soil minerals could increase biochar stability, which displays an important environmental significance of biochar for long-term carbon sequestration. Expand
Novel fold and capsid-binding properties of the λ-phage display platform protein gpD
The crystal structure of gpD, the capsid-stabilizing protein of bacteriophage λ, was solved at 1.1 Å resolution. Data were obtained from twinned crystals in space group P21 and refined with… Expand
Engineering of an N-acetylneuraminic acid synthetic pathway in Escherichia coli.
TLDR
This process offered an efficient fermentative method to produce NeuAc in microorganisms using glucose as carbon source and can be optimized for further improvement. Expand
Tissue deposition and residue depletion of cyadox and its three major metabolites in pigs after oral administration.
TLDR
Results showed that metabolites of CyX were quickly generated in swine tissues and the concentrations of QCA in kidney were higher than those of Cyx and other metabolites in all edible tissues. Expand
Short-term effects of rice straw biochar on sorption, emission, and transformation of soil NH4+-N
TLDR
In Anthrosols, biochar increased NH4+-N sorption, but it decreased N biotransformation (mineralization, nitrification, and assimilation) into NO3−-N, implying that the chemical sorption is a dominant process in the biochar-amended soil. Expand
Noncovalent interaction of dietary polyphenols with bovine hemoglobin in vitro: molecular structure/property-affinity relationship aspects.
TLDR
The affinities for bHB increased with increasing partition coefficients and decreased with increasing hydrogen bond donor and acceptor numbers of polyphenols, which suggested that the binding interaction was mainly caused by the hydrophobic force. Expand
Synthesis and biological evaluation of heterocyclic ring-substituted maslinic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B.
TLDR
A series of maslinic acid derivatives synthesized by introducing various fused heterocyclic rings at C-2 and C-3 positions exhibited a dramatic increase in inhibitory potency and selectivity, the two most potent PTP1B inhibitors 20 and 29 showed about 10-fold more potent than lead compound masLinic acid. Expand
Non-covalent interaction of dietary polyphenols with total plasma proteins of type II diabetes: molecular structure/property-affinity relationships.
  • J. Xiao, Yaru Zhao, +4 authors G. Kai
  • Chemistry, Medicine
  • Integrative biology : quantitative biosciences…
  • 31 October 2011
TLDR
The hydrophobic force played an important role in the binding interaction between polyphenols and IIDTPP. Expand
CdTe quantum dots (QDs) improve the affinities of baicalein and genistein for human serum albumin in vitro.
TLDR
The fluorescence intensities of HSA decreased remarkably with increasing concentration of QDs, and the binding affinities of baicalein and genistein for HSA increased with increasing QDs size. Expand
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