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LINKER was developed as an online server to assist biomedical researchers to design linker sequences for constructing functional fusion proteins. The program automatically generates a set of peptide sequences that are known to adopt extended conformations as determined by X-ray crystallography and NMR. In addition to the desired linker sequence length, the(More)
Prefabrication could provide various benefits for housing production, including lower the cost, improve the management efficiency and quality, ensure the safety, and realize sustainability. However, to fully acquire these benefits in real world construction process, challenges still exist on real-time tracing and tracking of the prefabrication components,(More)
This paper proposes a new nonvolatile Dual Interlocked Cell (NV-DICE) storage element. The cell includes a DICE latch and four backup ferroelectric capacitors. It can perform store automatically when the power is off abruptly and has high tolerance to SEU. READ and WRITE operations in this cell were simulated by HSIM. Single Event Upset (SEU) of the cell(More)
We present a hyper-heuristic algorithm for solving combinatorial black-box optimization problems. The algorithm named CMA-VNS stands for a hybrid of variants of Covariance Matrix Adaptation Evolution Strategy (CMA-ES) and Variable Neighborhood Search (VNS). The framework design and the design profiles of variants of CMA-VNS are introduced to enhance the(More)
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