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- Peter Mombaerts, Fan Wang, +5 authors Richard Axel
- Cell
- 1996
We have developed a genetic approach to visualize axons from olfactory sensory neurons expressing a given odorant receptor, as they project to the olfactory bulb. Neurons expressing a specific… (More)
- Fan Wang, Adriana Nemes, Monica Mendelsohn, Richard Axel
- Cell
- 1998
Olfactory neurons expressing a given odorant receptor project with precision to 2 of the 1800 glomeruli within the olfactory bulb to create a topographic map of odor quality. We demonstrate that… (More)
- Qing Liu, Utz Fischer, Fan Wang, Gideon Dreyfuss
- Cell
- 1997
Spinal muscular atrophy (SMA), one of the most common fatal autosomal recessive diseases, is characterized by degeneration of motor neurons and muscular atrophy. The SMA disease gene, termed Survival… (More)
Targeting of most nuclear proteins to the cell nucleus is initiated by interaction between the classical nuclear localization signals (NLSs) contained within them and the importin NLS receptor… (More)
- Isabella A. Graef, Fan Wang, +4 authors Gerald R Crabtree
- Cell
- 2003
Axon outgrowth is the first step in the formation of neuronal connections, but the pathways that regulate axon extension are still poorly understood. We find that mice deficient in calcineurin-NFAT… (More)
- Biola Maria Javierre, Oliver S. Burren, +36 authors Paul Flicek
- Cell
- 2016
Long-range interactions between regulatory elements and gene promoters play key roles in transcriptional regulation. The vast majority of interactions are uncharted, constituting a major missing link… (More)
- Wen Jun Song, Qi Qin, Jin Qiu, Can Hua Huang, Fan Wang, Choy Leong Hew
- Journal of virology
- 2004
Here we report the complete genome sequence of Singapore grouper iridovirus (SGIV). Sequencing of the random shotgun and restriction endonuclease genomic libraries showed that the entire SGIV genome… (More)
- Valentino Laquintana, Adriana Trapani, Nunzio Denora, Fan Wang, James M. Gallo, Giuseppe Trapani
- Expert opinion on drug delivery
- 2009
BACKGROUND
Malignant brain tumors are among the most challenging to treat and at present there are no uniformly successful treatment strategies. Standard treatment regimens consist of maximal… (More)
- Jieliang Chen, Wen Zhang, +7 authors Zhenghong Yuan
- Molecular therapy : the journal of the American…
- 2014
The hepatitis B virus (HBV) is a DNA virus that can cause chronic hepatitis B (CHB) in humans. Current therapies for CHB infection are limited in efficacy and do not target the pre-existing viral… (More)
- Jianhua Yin, Jiaxin Xie, +17 authors Guangwen Cao
- The American Journal of Gastroenterology
- 2011
OBJECTIVES:The objective of this study was to determine the association of 19 mutations with frequencies ≥10% in the core promoter region of hepatitis B virus (HBV) with chronic hepatitis B (CHB),… (More)