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FLT3 is a type III receptor tyrosine kinase that is thought to play a key role in hematopoiesis. Certain classes of FLT3 mutations cause constitutively activated forms of the receptor that are found in significant numbers of patients with acute myelogenous leukemia (AML). The mutations occur either in the activation loop, for example, as point mutations of(More)
OBJECTIVES To assess HIV and syphilis infection among men who have sex with men (MSM) in Chinese regions with historically low HIV prevalence. METHOD A cross-sectional survey was conducted in 20 cities or districts across 4 provinces, 2 autonomous regions, and a municipality. Socioeconomic/behavioral risk factors were measured. Blood samples were tested(More)
We develop and apply a previously undescribed framework that is designed to extract information in the form of a positive definite kernel matrix from possibly crude, noisy, incomplete, inconsistent dissimilarity information between pairs of objects, obtainable in a variety of contexts. Any positive definite kernel defines a consistent set of distances, and(More)
The uplift of the Qinghai-Tibetan Plateau (QTP) dramatically changed the topography and climate of Asia and affected the biodiversity of the plateau and its adjacent areas. However, the effects of the uplift on the dispersal, differentiation and adaptation of plants remain a puzzle when the date and processes of the uplift cannot be determined with(More)
PURPOSE To determine corneal biomechanical properties in patients with high myopia. DESIGN Observational study. METHODS High myopia patients (n=45, age: 37.0+/-12.6 years) with refractive errors of spherical equivalent (SE) greater than -9.00D were recruited in this study along with healthy subjects (n=90, age: 33.7+/-12.4 years) with refractive errors(More)
Dissolved organic matter (DOM) sampled from municipal landfill leachate of different ages with/without anoxic or aerobic treatment, was intensively fractionated via size exclusion chromatography (SEC) and hydrophobic resins, and was studied with fluorescence excitation and emission matrix (EEM). Six fluorophores with multiple EEM peaks (fluorophore A-F)(More)
BACKGROUND No new estimates of HIV infection have been available for China since 2003. However, since then, data availability has increased dramatically. OBJECTIVES To use internationally recommended methods to make new estimates of the number of people exposed to HIV in China, the number living with HIV, and the number of new HIV infections and deaths in(More)
PURPOSE To investigate changes in Ocular Response Analyzer parameters after myopic LASIK. METHODS Thirty myopic patients (60 eyes) undergoing bilateral LASIK were studied prospectively. Corneal hysteresis, corneal resistance factor, Goldmann-correlated intraocular pressure (IOPg), and corneal-compensated IOP (IOPcc) measurements were obtained with the(More)
PURPOSE To determine if corneal hysteresis (CH) was associated with increased central corneal thickness (CCT) induced by wearing soft contact lenses during eye closure. DESIGN A prospective laboratory investigation. METHODS CCT was measured with a modified optical coherence tomography (OCT), and CH was measured with a Reichert Ocular Response Analyzer(More)