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Primordial germ cells (PGCs) are the precursors of gametes responsible for genetic transmission to the next generation. They provide an ideal system for cryopreservation and restoration of biodiversity. Recently, considerable attention has been raised to visualize, isolate and transplant PGCs within and between species. In fish, stable PGC visualization in(More)
Single and repeated sports-related mild traumatic brain injury (mTBI), also referred to as concussion, can result in chronic post-concussive syndrome (PCS), neuropsychological and cognitive deficits, or chronic traumatic encephalopathy (CTE). However PCS is often difficult to diagnose using routine clinical, neuroimaging or laboratory evaluations, while CTE(More)
Virtual Probe (VP), proposed for characterization of spatial variations and for test time reduction, can effectively reconstruct the spatial pattern of a test item for an entire wafer using measurement values from only a small fraction of dies on the wafer. However, VP calculates the spatial signature of each test item separately, one item at a time,(More)
OBJECTIVE Urothelial carcinoma (UC) of the kidney is a relatively rare but aggressive form of kidney cancer. Differential diagnosis of renal UC from renal cell carcinoma (RCC) can be difficult, but is critical for correct patient management. We aimed to use global gene expression profiling to identify genes specifically expressed in urothelial carcinoma(More)
The problem of inferring a user's intentions in Machine–Human Interaction has been the key research issue for providing personalized experiences and services. In this paper, we propose novel approaches on modeling and inferring user's actions in a computer. Two linguistic features – keyword and concept features – are extracted from the semantic context for(More)
In maize (Zea mays), abscisic acid (ABA)-induced H(2)O(2) production activates a 46 kDa mitogen-activated protein kinase (p46MAPK), and the activation of p46MAPK also regulates the production of H(2)O(2). However, the mechanism for the regulation of H(2)O(2) production by MAPK in ABA signalling remains to be elucidated. In this study, four reactive oxygen(More)
—The discovery of patterns and correlations hidden in the test data could help reduce test time and cost. In this paper, we propose a methodology and supporting statistical regression tools that can exploit and utilize both spatial and inter-test-item correlations in the test data for test time and cost reduction. We first describe a statistical regression(More)
In this paper, we investigate the problem of optimizing complex multivariate performance measures to learn classifiers for pattern classification problems. For the first time, the multi-kernel learning is considered to construct a classifier to optimize a given nonlinear and non-smooth multivariate classifier performance measure. We estimate and optimize(More)
Transactivation response DNA-binding protein 43 (TDP-43) proteinopathy has recently been reported in chronic traumatic encephalopathy, a neurodegenerative condition linked to prior history of traumatic brain injury (TBI). While TDP-43 appears to be vulnerable to proteolytic modifications under neurodegenerative conditions, the mechanism underlying the(More)
—It is known that statistical analysis of test data can help screen potential test escapes without additional physical measurements. Based on analysis of production test data, this paper focuses on feature engineering for statistical tests to screen test escapes. The features are engineered in two aspects: development of effective features and(More)