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The ensemble Kalman filter (EnKF) uses an ensemble of short-range forecasts to estimate the flow-dependent background error covariances required in data assimilation. The feasibility of the EnKF for convective-scale data assimilation has been previously demonstrated in perfect-model experiments using simulated observations of radial velocity from a(More)
The NS5B RNA-dependent RNA polymerase encoded by hepatitis C virus (HCV) plays a key role in viral replication. Reported here is evidence that HCV NS5B polymerase acts as a functional oligomer. Oligomerization of HCV NS5B protein was demonstrated by gel filtration, chemical cross-linking, temperature sensitivity, and yeast cell two-hybrid analysis.(More)
spxB-encoded pyruvate oxidase is a major virulence factor of Streptococcus pneumoniae. During aerobic growth, SpxB synthesizes H2O2 and acetyl phosphate, which play roles in metabolism, signalling, and oxidative stress. We report here the first cis- and trans-acting regulatory elements for spxB transcription. These elements were identified in a genetic(More)
In this paper we present experimental data that shows the dependence of copper dishing and oxide erosion on pitch and pattern density, as well as on polishing process parameters including table speed, down force, and process sequence. Specifically, the data shows that the degree of dishing and erosion strongly depends on both the processing parameters and(More)
Osteopontin (OPN), cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF) are overexpressed in various experimental models of malignancy. However, the correlation and role of the three molecules in gastric cancer is unclear. In the present study, we found that OPN, COX-2 and VEGF were overexpressed in 53 cancerous tissues with gastric cancer(More)
Face recognition with single training sample has the problem that the sample is single and face pattern is changeable. The rate of traditional face recognition methods declines seriously in the case of single training sample. Thus, studying the face recognition method which is appropriate for single training sample is challenging in face recognition field.(More)
Leptin is an adipocyte-derived hormone that acts as a major regulator for food intake and energy homeostasis. Leptin deficiency or resistance can result in profound obesity, diabetes, and infertility in humans. Since its discovery, our understanding of leptin's biological functions has expanded from anti-obesity to broad effects on reproduction,(More)
The NS5B RNA-dependent RNA polymerase encoded by the hepatitis C virus (HCV) is a key component of the viral replicase. Reported here is the three-dimensional structure of HCV NS5B polymerase, with the highlight on its C-terminal folding, determined by X-ray crystallography at 2.1-A resolution. Structural analysis revealed that a stretch of C-terminal(More)
BACKGROUND Since 2008, a progressive pneumonia has become prevalent in broilers and laying hens. This disease occurrs the first day after hatching and lasts more than 30 days, resulting in approximately 70% morbidity and 30% mortality in broilers. The objective of this study was to isolate and identify the pathogens that are responsible for the progressive(More)