Falk Schmidt

Learn More
15 The Earth System Science Partnership (ESSP) was established in 2001 by four global environmental change (GEC) research programmes: DIVERSITAS, IGBP, IHDP and WCRP. ESSP facilitates the study of the Earth's environment as an integrated system in order to understand how and why it is changing, and to explore the implications of these changes for global and(More)
2013. Missing links in global water governance: a processes-oriented analysis. ABSTRACT. Over the past decade, the policy and scholarly communities have increasingly recognized the need for governance of water-related issues at the global level. There has been major progress in the achievement of international goals related to the provision of basic water(More)
Despite evidence for a conserved role of thyroid-stimulating hormone (TSH) in regulating vertebrate thyroid function, molecular data on thyroid responses to TSH are mainly limited to mammalian species. In this study, we examined histological and molecular changes in the thyroid of Xenopus laevis tadpoles during a 12-day treatment with 20mg/l perchlorate(More)
Global water problems are likely to increase in severity, rendering existing governance approaches unable to cope with the resulting problems. We inquire into the relationship between global water governance structures, particularly those involving the United Nations, and look at how those structures are likely to respond to and shape projected water(More)
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease in which environmental exposures like virus infection and UV-irradiation trigger activation of the innate and adaptive immune system in genetically predisposed individuals. Heterozygous mutations of the 3' repair exonuclease 1 (TREX1) are associated with SLE. Biallelic mutations in(More)
Ribonuclease H2 plays an essential role for genome stability as it removes ribonucleotides misincorporated into genomic DNA by replicative polymerases and resolves RNA/DNA hybrids. Hypomorphic loss-of-function mutations in the genes encoding the three RNase H2 subunits cause the type I interferonopathies Aicardi-Goutières syndrome (AGS) and systemic lypus(More)
The views expressed in this publication are those of the author(s). Publication does not imply endorsement by the UNU-EHS or the United Nations University of any of the views expressed. 1 2 Acknowledgements We would like to express our appreciation to the organisers of the international conference 'Towards Sustainable Global Health' of which this SOURCE(More)
  • 1