Falk Georges Bechara

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Michael Sand91
Peter Altmeyer87
Thilo Gambichler51
Daniel Sand44
Klaus Hoffmann43
88Michael Sand
80Peter Altmeyer
48Thilo Gambichler
47Schapoor Hessam
43Klaus Hoffmann

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2002
2017
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In vivo optical coherence tomography of basal cell carcinoma.
BACKGROUND Optical coherence tomography (OCT) is a promising non-invasive imaging technique that has not systematically been studied in skin cancer such as basal cell carcinoma (BCC). OBJECTIVE We aimed, first, to describe the in vivo histologic features of BCC by using OCT, and second, to find out whether it is possible to differentiate BCC subtypes by… (More)
Characterization of benign and malignant melanocytic skin lesions using optical coherence tomography in vivo.
BACKGROUND Although optical coherence tomography (OCT) is a promising noninvasive imaging technique for the micromorphology of the skin, OCT has not been studied systematically in skin cancer such as malignant melanoma (MM). OBJECTIVE We sought to visualize and characterize melanocytic skin lesions (MSL) by using OCT in vivo, compare OCT features of… (More)
Bicentre experience in the treatment of severe generalised atopic dermatitis with extracorporeal photochemotherapy.
Pilot studies have shown an improvement of atopic dermatitis in approximately 65% of patients during extracorporeal photopheresis (ExP) therapy. The purpose of the present clinical trial was to investigate the response to ExP by controlling clinical and laboratory parameters during short term ExP therapy in patients with severe generalised atopic… (More)
Serum calcitonin negative Medullary thyroid carcinoma
BACKGROUND Medullary thyroid carcinomas (MTC) constitute about 5 to 7% of thyroid neoplasms. They originate from parafollicular C cells which produce Calcitonin, a hormone which has an impact on calcium metabolism and represents the biochemical activity of MTC. In rare cases pre-operative serum calcitonin can be negative. CASE PRESENTATION We report on a… (More)
Inflammation induced changes in the expression levels of components of the microRNA maturation machinery Drosha, Dicer, Drosha co-factor DGRC8 and Exportin-5 in inflammatory lesions of hidradenitis suppurativa patients.
BACKGROUND The inflammatory pathogenesis behind the debilitating chronic inflammatory skin disorder hidradenitis suppurativa (HS) is poorly understood. Deregulation of microRNAs (miRNAs) may contribute to the pathogenesis and chronic inflammation in autoimmune and inflammatory diseases. However, there are no data on the expression or function of miRNAs in… (More)
Correlation of inflammatory serum markers with disease severity in patients with hidradenitis suppurativa (HS).
BACKGROUND Data regarding the association of routinely obtained serum markers of inflammation, namely C-reactive protein (CRP), white blood cell count, and neutrophil count, with disease severity of hidradenitis suppurativa (HS) according to a scoring system have not been reported to our knowledge. OBJECTIVE We sought to evaluate these inflammatory serum… (More)
Acne Inversa: Evaluating Antimicrobial Peptides and Proteins
BACKGROUND Acne inversa is a chronic, suppurative relapsing inflammatory skin disease that primarily affects the axillae, perineum and inframammary regions. Evidence suggests that the innate immune system is involved in the pathogenesis of acne inversa. OBJECTIVE To investigate the role of the innate immune system in acne inversa. METHODS Skin biopsies… (More)
Diagnostic value of hyperbilirubinemia as a predictive factor for appendiceal perforation in acute appendicitis.
BACKGROUND Appendiceal perforation in patients with acute appendicitis may cause a variety of potentially life-threatening complications. Escherichia coli endotoxin has been shown to impact physiological bile flow in vivo. This had led to the theory that hyperbilirubinemia in patients with appendicitis may have a predictive potential for the preoperative… (More)
Hyaluronic acid new formulation: experience in HIV-associated facial lipoatrophy.
BACKGROUND Facial lipoatrophy (FLA) is a stigmatizing complication of antiretroviral therapy in patients with human immunodeficiency virus (HIV) infection. OBJECTIVES To evaluate the efficacy and safety of facial volume restoration in patients with HIV-associated FLA, using a novel long-lasting, hyaluronic acid high-density formulation. METHODS… (More)