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BACKGROUND
Power distributions appear in numerous biological, physical and other contexts, which appear to be fundamentally different. In biology, power laws have been claimed to describe the distributions of the connections of enzymes and metabolites in metabolic networks, the number of interactions partners of a given protein, the number of members in… (More)

We present a complete parametric analysis of stability properties and dynamic regimes of an ODE model in which the functional response is a function of the ratio of prey and predator abundances. We show the existence of eight qualitatively different types of system behaviors realized for various parameter values. In particular, there exist areas of… (More)

Selection systems and the corresponding replicator equations model the evolution of repli-cators with a high level of abstraction. In this paper we apply novel methods of analysis of selection systems to the replicator equations. To be suitable for the suggested algorithm the interaction matrix of the replicator equation should be transformed; in particular… (More)

BACKGROUND
The size distribution of gene families in a broad range of genomes is well approximated by a generalized Pareto function. Evolution of ensembles of gene families can be described with Birth, Death, and Innovation Models (BDIMs). Analysis of the properties of different versions of BDIMs has the potential of revealing important features of genome… (More)

The population dynamics of predator-prey systems in the presence of patch-specific predators are explored in a setting where the prey population has access to both habitats. The emphasis is in situations where patch-prey abundance drives prey dispersal between patches, with the fragile prey populations, i.e. populations subject to the Allee effect. The… (More)

BACKGROUND
Oncolytic viruses that specifically target tumor cells are promising anti-cancer therapeutic agents. The interaction between an oncolytic virus and tumor cells is amenable to mathematical modeling using adaptations of techniques employed previously for modeling other types of virus-cell interaction.
RESULTS
A complete parametric analysis of… (More)

A class of models of biological population and communities with a singular equilibrium at the origin is analyzed; it is shown that these models can possess a dynamical regime of deterministic extinction, which is crucially important from the biological standpoint. This regime corresponds to the presence of a family of homoclinics to the origin, so-called… (More)

A model of the dynamics of natural rotifer populations is described as a discrete nonlinear map depending on three parameters, which reflect characteristics of the population and environment. Model dynamics and their change by variation of these parameters were investigated by methods of bifurcation theory. A phase–parametric portrait of the model was… (More)

MOTIVATION
In our previous studies, we developed discrete-space birth, death and innovation models (BDIMs) of genome evolution. These models explain the origin of the characteristic Pareto distribution of paralogous gene family sizes in genomes, and model parameters that provide for the evolution of these distributions within a realistic time frame have… (More)