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- Mirjam J Eberhardt, Mária Dux, +22 authors Milos R Filipovic
- Nature communications
- 2014
Nitroxyl (HNO) is a redox sibling of nitric oxide (NO) that targets distinct signalling pathways with pharmacological endpoints of high significance in the treatment of heart failure. Beneficial HNO… (More)
- Jorge Montanari, A. P. Perez, +6 authors E. L. Romero
- International journal of pharmaceutics
- 2007
Hydrophobic ([tetrakis(2,4-dimetil-3-pentyloxi)-phthalocyaninate]zinc(II)) (ZnPc) and hydrophilic ([tetrakis(N,N,N-trimethylammoniumetoxi)-phthalocyaninate]zinc(II) tetraiodide) (ZnPcMet)… (More)
- Graciela E Alluisetti, Alejandra E. Almaraz, ValentÃn Tomás Amorebieta, Fabio Doctorovich, José Antonio Olabe
- Journal of the American Chemical Society
- 2004
The catalytic disproportionation of NH(2)OH has been studied in anaerobic aqueous solution, pH 6-9.3, at 25.0 degrees C, with Na(3)[Fe(CN)(5)NH(3)].3H(2)O as a precursor of the catalyst,… (More)
- Kiran Sirsalmath, Sebastian A Suarez, DamÃan E Bikiel, Fabio Doctorovich
- Journal of inorganic biochemistry
- 2013
A group of Piloty's acid (N-hydroxybenzenesulfonamide) derivatives were synthesized and fully characterized in order to assess the rates and pH of HNO (azanone, nitroxyl) donation in aqueous media.… (More)
- Mariana Hamer, Sebastian A Suarez, +4 authors Fabio Doctorovich
- Inorganic chemistry
- 2015
The reduction of NO(•) to HNO/NO(-) under biologically compatible conditions has always been thought as unlikely, mostly because of the negative reduction potential: E°(NO(•),H(+)/HNO) = -0.55 V vs… (More)
- Laura L. Perissinotti, Adrian Gustavo Turjanski, Dario A. Estrin, Fabio Doctorovich
- Journal of the American Chemical Society
- 2005
We report an investigation of the reaction between (S)-nitroso-l-cysteine ethyl ester and l-cysteine ethyl ester as a model of physiologically relevant transnitrosation processes. Our theoretical and… (More)
- Sebastian A Suarez, Nicolás I Neuman, +8 authors Fabio Doctorovich
- Journal of the American Chemical Society
- 2015
The role of NO in biology is well established. However, an increasing body of evidence suggests that azanone (HNO), could also be involved in biological processes, some of which are attributed to NO.… (More)
- Fernando M Baidanoff, Santiago A. Plano, Fabio Doctorovich, Sebastian A Suarez, Diego Andrés Golombek, Juan José Chiesa
- Journal of neurochemistry
- 2014
Most physiological processes in mammals are synchronized to the daily light:dark cycle by a circadian clock located in the hypothalamic suprachiasmatic nucleus. Signal transduction of light-induced… (More)
- Luciana Capece, Marcelo A. Marti, Alejandro Crespo, Fabio Doctorovich, Dario A. Estrin
- Journal of the American Chemical Society
- 2006
Heme proteins are found in all living organisms and are capable of performing a wide variety of tasks, requiring in many cases the binding of diatomic ligands, namely, O(2), CO, and/or NO. Therefore,… (More)
- Sebastian A Suarez, DamÃan E Bikiel, Diana E. Wetzler, Marcelo A. Marti, Fabio Doctorovich
- Analytical chemistry
- 2013
Azanone (HNO, nitroxyl) is a highly reactive and short-lived compound with intriguing and highly relevant properties. It has been proposed to be a reaction intermediate in several chemical reactions… (More)