Fabienne Mauxion

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We have identified a DNA binding protein, named BETA, that interacts with the same (B) transcriptional regulatory sequence as the known transcription factor NF-kappa B. BETA is found only in gray matter throughout the brain, and not in a variety of other rat tissues. Two binding sites for BETA are present adjacent to the promoter of the rat proenkephalin(More)
While BTG2 plays an important role in cellular differentiation and cancer, its precise molecular function remains unclear. BTG2 interacts with CAF1 deadenylase through its APRO domain, a defining feature of BTG/Tob factors. Our previous experiments revealed that expression of BTG2 promoted mRNA poly(A) tail shortening through an undefined mechanism. Here we(More)
The cr and /3 chains constituting the TCR are expressed specifically on T lym-phoid cells after genomic rearrangements have led to the assembly of functional a and /3 chain genes (1). T cell-specific transcriptional activation of the unrearranged gene segments is considered to be a prerequisite for the recombination process that apparently uses the same(More)
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