Fabian León-Vargas

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This paper addresses the design of blood glucose control during the postprandial period for Type 1 diabetes patients. An artificial pancreas for ambulatory purposes has to deal with the delays inherent to the subcutaneous route, the carbohydrate intakes, the metabolic changes, the glucose sensor errors and noise, and the insulin pump constraints. A time(More)
Traditional type 1 diabetes therapies are prone to show poor glucose regulation especially in the postprandial period owing to both physiological and technological limitations. Although a closed-loop controller for glucose regulation has to be tuned to minimize the postprandial excursion and avoid late hypoglycemia, the intrinsic limitations of the problem(More)
This article presents a new simulation tool for designing and testing blood glucose control algorithms in patients with type 1 diabetes. The control algorithms can be designed and implemented either with textual or graphical programming languages or by importing them from several frameworks. Realistic scenarios and protocols can be customized and built(More)
OBJECTIVE Set-inversion-based prandial insulin delivery is a new model-based bolus advisor for postprandial glucose control in type 1 diabetes mellitus (T1DM). It automatically coordinates the values of basal-bolus insulin to be infused during the postprandial period so as to achieve some predefined control objectives. However, the method requires an(More)
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